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Noebels JL, Avoli M, Rogawski MA, et al., editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.

  • This title is an author manuscript version first made accessible on the NCBI Bookshelf website July 2, 2012.

This title is an author manuscript version first made accessible on the NCBI Bookshelf website July 2, 2012.

Cover of Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition.

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Table 4Expression of anti-apoptotic proteins in TLE brain tissue

Increased
  1. Bcl-2, Bcl-xL* and Bcl-w (hippocampus or neocortex)
  2. Akt phosphorylation (hippocampus)
  3. X-linked IAP binding to caspase-7 (hippocampus)
Decreased
  1. MDM2 (p53 negative regulator)
*

Bcl-xL was increased in neocortex but not in hippocampus

From: Cell death and survival mechanisms after single and repeated brief seizures

Copyright © 2012, Michael A Rogawski, Antonio V Delgado-Escueta, Jeffrey L Noebels, Massimo Avoli and Richard W Olsen.

All Jasper's Basic Mechanisms of the Epilepsies content, except where otherwise noted, is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported license, which permits copying, distribution and transmission of the work, provided the original work is properly cited, not used for commercial purposes, nor is altered or transformed.

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