TABLE 5.2Effect of C. sinensis and C. militaris on Sexual and Reproductive Function

Cordyceps ModelDaily Dose or ConcentrationStudy DurationEffectsReferences
Cultured C. sinensisFruiting bodiesCastrated rats0.5-2.0 g/kg21 daysShortened penis erection latency and mount latencyJi et al. 2009
 MyceliaMale mice0.02 or 0.2 mg/g7 daysPromoted the production of plasma testosteroneHsu et al. 2003b, Huang et al. 2004
  Primary mouse Leydig cells, and MA-10 mouse Leydig tumor cells3 mg/mL3 hoursPromoted testosterone release, and suppressed hCG and dbcAMP-stimulated testosterone productionsHuang et al. 2001a and 2001b; Hsu etal. 2003a and 2003b
Cultured C. militarisMyceliaMale rast1% and 5% of diet6 weeksImproved sperm count and percentages of motile sperm cells; elevated plasma testosterone and estradiol-17 concentrationChang et al. 2008a
  Subfertile boars0.5% of diet (10 g/boar)2 monthsImproved sperm volume, morphology, and serum testosteroneLin et al. 2007

From: Chapter 5, Cordyceps as an Herbal Drug

Cover of Herbal Medicine
Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.
Benzie IFF, Wachtel-Galor S, editors.
Boca Raton (FL): CRC Press/Taylor & Francis; 2011.
Copyright © 2011 by Taylor and Francis Group, LLC.

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