From: Genetics of Prostate Cancer (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 1. Relative Risk (RR) Related to Family History of Prostate Cancera
| Risk Group | RR for Prostate Cancer (95% CI) |
|---|---|
| Brother(s) with prostate cancer diagnosed at any age | 3.14 (2.37–4.15) |
| Father with prostate cancer diagnosed at any age | 2.35 (2.02–2.72) |
| One affected FDR diagnosed at any age | 2.48 (2.25–2.74) |
| Affected FDRs diagnosed <65 y | 2.87 (2.21–3.74) |
| Affected FDRs diagnosed ≥65 y | 1.92 (1.49–2.47) |
| Second-degree relatives diagnosed at any age | 2.52 (0.99–6.46) |
| Two or more affected FDRs diagnosed at any age | 4.39 (2.61–7.39) |
CI = confidence interval; FDR = first-degree relative.
aAdapted from Kiciński et al.[14]