Table 2pH regulators and inhibitors

pH RegulatorspH Regulators
1) V-ATPase (Vacuolar proton pump)1A) Bafilomycin
1B) Oximidine
2) Lactaate/H+Symport [MCT]2A) α-cyano-4-hydroxylcinnamic acid [CNCN]
2B) Lonidamine
2C) Quercetin
3) NA+/H+ exchanger [NHE]3A) Amiloride
3B) Cariporide
4) CL-/HCO3 - [BCT]4A) Cariporide
4B) 4,4'-diisocyanatostilbene-2,2'-disulfonic acid [DIDS]
Mitochondrial Metabolic Inhibitors
1) Lonidamine 2) Metaiodobenzylguanidine [MIBG]

From: Influence of Tumor Microenvironment on Thermoresponse: Biologic and Clinical Implications

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