Table 6Results for Primary and Secondary Outcomes: Means (SD)

OutcomeIntervention DAControl Non-DAAdjusted P valuea
Baseline n = 471 wk n = 291 mo n = 27Baseline n = 511 wk n = 341 mo n = 31
LVAD knowledge (primary outcome), mean (SD)b,c45.6 (22.2) 67.8 (15.6) 64.3 (14.0)43.8 (18.3) 59.3 (12.4) 60.7 (12.0).01/.47
Decisional conflictb,d23.1 (20.7)15.7 (11.8)---29.3 (19.3)17.4 (14.7)---.12/.79
 Informed subscale 26.5 (26.2) 16.1 (13.0)--- 35.0 (23.9) 15.2 (13.6)---.04/.81
 Values clarity subscale26.3 (24.4)14.1 (14.1)---29.9 (24.4)17.9 (17.7)---.44/.43
 Support subscale16.5 (17.4)11.2 (12.1)---20.3 (16.1)15.7 (14.2)---.17/.23
 Uncertainty subscale23.6 (26.1)21.0 (17.0)---32.2 (26.1)20.1 (21.2)---.07/.73
 Effective decision subscale---16.2 (14.6)------17.4 (15.2)---.89
Preparedness for decision-makingb---86.9 (15.1)------81.8 (17.4)---.27
Satisfaction with decision-making processb------75.6 (23.7)------76.8 (20.0)1.00
Decisional regretb------11.5 (13.3)------12.9 (16.6).95
Shared decision-making (CollaboRATE)b---88.4 (19.3)90.4 (14.3)---89.6 (15.6)89.8 (17.2).99/.94
SDM-9b---84.8 (16.8)87.5 (12.8)---84.3 (13.6)85.2 (15.0).65/.74
Match in control preferences over time, %48%52%1.0
Envision life with LVAD: somewhat/easy to picture, %---93%------76%---.3
Envision life with LVAD: very close to what I expected, %------75%------43%.08
Perceived likelihood of transplant, %---62%63%---67%48%.60/.27
Survival estimate after LVAD implant, mean (SD), y---10.17 (7.14)------9.7 (9.8)---.45
Satisfaction With Life Scale, mean (SD)e22.8 (6.6)--- 27.9 (5.7) 20.4 (7.2)--- 22.9 (6.6) .13/.006
Quality of life, mean (SD)f 55.8 (24.0) --- 81.0 (3.7) 43.1 (24.5) --- 69.1 (3.5) .01/.03
Preferred treatment (Intend to choose/chose LVAD), %61%75%85%62%79%78%.77/.74
Advanced directive (yes), %------68%------44%.12

Abbreviations: LVAD, left ventricular assist device; SDM, shared decision-making.

aP values refer to significant differences observed between trial arms at the relevant time points listed in the row. If measures were taken at all 3 time points (LVAD knowledge only), P values refer to differences observed at 1 week and 1 month (P values listed before the slash denote 1-week results; results listed after the slash denote 1-month results). Results listed in boldface type were statistically significant.

bOut of 0-100 scale. Higher scores indicate more positive outcomes, unless indicated as reversed.

cModel included fixed effects for arm, time (discrete), and arm × time interaction term and adjusted for baseline KS score and health literacy score.

dScale is reversed.

eOut of 0-30 scale. Higher scores indicate higher satisfaction with life.

fThere was a significant increase in QOL scores for both the non-DA (P = .03) and the DA group (P = .003). While this difference is significant, the change from baseline to 1 month is not significantly different between arms. On average, QOL scores increased by 26.76 points for the non-DA group compared with 25.07 points for the DA group.

From: Does a Decision Aid Help Patients Learn about Their Treatment Options for Advanced Heart Failure?

Cover of Does a Decision Aid Help Patients Learn about Their Treatment Options for Advanced Heart Failure?
Does a Decision Aid Help Patients Learn about Their Treatment Options for Advanced Heart Failure? [Internet]
Blumenthal-Barby J, Kostick K, Bruce C, et al.
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