Table 1Malignant and Combined Incidences of Tumors

RatMouse
Tissue SiteMalignantCombinedMalignantCombined
Lung↑F*M↑M, ↑F↑M, ↑F
Adrenal gland–↑F––
Skin–––↑M
Lymphatic system––↑F–

Combined = combined incidence of benign and malignant tumors.

↑ = Significant increase; F = in females; M = in males.

* = Considered to be evidence of antimony trioxide carcinogenicity based on multiple factors, although the increase in incidence was not statistically significant (NTP 2017).

– = No exposure-related increase in tumors.

From: Antimony Trioxide

Cover of 15th Report on Carcinogens
15th Report on Carcinogens [Internet].
National Toxicology Program.
Research Triangle Park (NC): National Toxicology Program; 2021 Dec 21.
Copyright Notice

This is a work of the US government and distributed under the terms of the Public Domain

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.