Table 7, WeeFIM and PROMIS Parent Proxy Scores at 6 Months and 12 Months After Symptom Onset by AFM Subtype - Does Plasma Exchange Help Improve Physical Function in Children with Transverse Myelitis?

	Gray-matter–isolated AFM	Mixed-matter–isolated AFM	P value
6 mo after onset
WeeFIM scores
Total	108 (83-125)	3	92.5 (49-140)	4	32 (20-140)	4	0	.86	.4
Motor subset	83 (63-92)	3	64 (26-105)	4	19 (15-105)	4	0	.86	.38
PROMIS Parent Proxy scores
Mobility subset	36 (31-40)	5	20 (8-32)	2	24 (8-38)	7	0	.19	.12
Upper Extremity subset	26 (17-40)	5	28 (18-38)	2	36 (23-40)	7	0	1.00	.14
12 mo after onset
WeeFIM scores
Total	122 (114-128)	3	74 (54-140)	7	67 (39-140)	7	0	.25	.18
Motor subset	94 (86-96)	3	51 (31-105)	7	37 (15-105)	7	0	.18	.14
PROMIS Parent Proxy scores
Mobility subset	34.5 (26-40)	6	20 (10-39)	5	34 (13-40)	7	0	.31	.31
Upper Extremity subset	34 (22-40)	4	32.5 (8-39)	4	37.5 (29-40)	6	0	.77	.51

Gray-matter–isolated AFM

Mixed-matter–isolated AFM

P value

I. Corticosteroids

II. No corticosteroids

III. Corticosteroids

IV. No corticosteroids

I vs II

I vs III

Median (range)

6 mo after onset

WeeFIM scores

Total

108 (83-125)

92.5 (49-140)

32 (20-140)

.86

Motor subset

83 (63-92)

64 (26-105)

19 (15-105)

.86

.38

PROMIS Parent Proxy scores

Mobility subset

36 (31-40)

20 (8-32)

24 (8-38)

.19

.12

Upper Extremity subset

26 (17-40)

28 (18-38)

36 (23-40)

1.00

.14

12 mo after onset

WeeFIM scores

Total

122 (114-128)

74 (54-140)

67 (39-140)

.25

.18

Motor subset

94 (86-96)

51 (31-105)

37 (15-105)

.18

.14

PROMIS Parent Proxy scores

Mobility subset

34.5 (26-40)

20 (10-39)

34 (13-40)

.31

Upper Extremity subset

34 (22-40)

32.5 (8-39)

37.5 (29-40)

.77

.51

From: Does Plasma Exchange Help Improve Physical Function in Children with Transverse Myelitis? – The CAPTURE Study

Cover of Does Plasma Exchange Help Improve Physical Function in Children with Transverse Myelitis? – The CAPTURE Study

Does Plasma Exchange Help Improve Physical Function in Children with Transverse Myelitis? – The CAPTURE Study [Internet].

Greenberg BM, Pardo C, Recio A, et al.

Washington (DC): Patient-Centered Outcomes Research Institute (PCORI); 2021 Feb.

This book is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License which permits noncommercial use and distribution provided the original author(s) and source are credited. (See https://creativecommons.org/licenses/by-nc-nd/4.0/

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Table 7WeeFIM and PROMIS Parent Proxy Scores at 6 Months and 12 Months After Symptom Onset by AFM Subtype