| Study | Population | Intervention | Comparison | Comments |
|---|---|---|---|---|
|
RCT Sweden |
N=665 Baseline severity: More severe Mean age (years): 48.5 Sex (% female): 72 Ethnicity (% BME): NR |
Pure medication management Therapeutic drug monitoring (TDM). All patients were treated with sertraline. Plasma levels of sertraline and desmethylsertrali ne were determined at weeks 4 and 12 and reported back to the GP for continued discussion with the patients. Intervention included monitoring for side effects | Standard care |
Duration of programme contact (in months): 6 Outcomes:
|
|
RCT Saudi Arabia |
N=239 Baseline severity: More severe Mean age (years): NR Sex (% female): 55 Ethnicity (% BME): NR |
Pure medication management Pharmacist intervention involving assessing patients’ beliefs and knowledge about antidepressants and distribution of a decision aid to patients | Standard care |
Duration of programme contact (in months): 3 Outcomes:
|
|
RCT US |
N=63 Baseline severity: Less severe Mean age (years): 38 Sex (% female): 84 Ethnicity (% BME): 8 |
Pure medication management Pharmacist-guided education and monitoring (PGEM) included assessing patient’s antidepressant knowledge and beliefs, adverse effects and other concerns, treatment goals, and how the medication was being used, reviewing of current adherence, and any new adverse effects and concerns | Standard care |
Duration of programme contact (in months): 3 Outcomes:
|
|
RCT Spain |
N=179 Baseline severity: Less severe Mean age (years): 46.6 Sex (% female): 75 Ethnicity (% BME): NR |
Pure medication management Community pharmacist intervention included provision of an educational intervention aimed at improving patients’ knowledge of antidepressants and awareness of the importance of adherence, and monitoring of patient progress (improvement, appearance of side effects, or queries) | Standard care |
Duration of programme contact (in months): 6 Outcomes:
|
|
RCT US |
N=70 Baseline severity: More severe Mean age (years): 76 Sex (% female): 77 Ethnicity (% BME): 29 |
Pure medication management Treatment Initiation and Participation (TIP) programme, included reviewing symptoms and antidepressant therapy regimen and conducting a barriers assessment, defining personal treatment goal, provision of education about depression and antidepressants, discussing barriers to adherence, creating an adherence strategy, and encouraging the patient to talk directly with the primary care physician about treatment | Standard care |
Duration of programme contact (in months): 2 Outcomes:
|
BME: black minority ethnic; N: number; NR: not reported; RCT: randomised controlled trial
From: Service delivery Models and settings for delivery of services
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