Table 3, Summary of included studies for Comparison 2: Collaborative care versus standard care for relapse prevention - Service delivery Models and settings for delivery of services

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Table 3Summary of included studies for Comparison 2: Collaborative care versus standard care for relapse prevention

Study	Population	Intervention	Comparison	Comments
Katon 2001 RCT US	N=386 Baseline severity: Recovered but at high risk of relapse (<4 DSM-IV MDD symptoms and a history of ≥3 episodes of MDD or dysthymia or 4 residual depressive symptoms but mean SCL-20 depression score < 1.0 and a history of MDD/dysthymia) Mean age (years): 46 Sex (% female): 74 Ethnicity (% BME): 10	Simple collaborative care Collaborative care component score: 9	Standard care	Duration of programme contact (in months): 12 Outcomes: Relapse at 12 months Antidepressant use at 6 months Antidepressant use at 12 months Discontinuation at 12 months

Study

Population

Intervention

Comparison

Comments

Katon 2001

RCT

N=386

Baseline severity: Recovered but at high risk of relapse (<4 DSM-IV MDD symptoms and a history of ≥3 episodes of MDD or dysthymia or 4 residual depressive symptoms but mean SCL-20 depression score < 1.0 and a history of MDD/dysthymia)

Mean age (years): 46

Sex (% female): 74

Ethnicity (% BME): 10

Simple collaborative care

Collaborative care component score: 9

Standard care

Duration of programme contact (in months): 12

Outcomes:

Relapse at 12 months
Antidepressant use at 6 months
Antidepressant use at 12 months
Discontinuation at 12 months

: BME: black minority ethnic; DSM: diagnostic statistical manual; MDD: major depressive disorder; N: number; NR: not reported; RCT: randomised controlled trial; SCL-20: symptom checklist

From: Service delivery Models and settings for delivery of services

Cover of Service delivery Models and settings for delivery of services

Service delivery Models and settings for delivery of services: Depression in adults: Evidence review A.

NICE Guideline, No. 222.

London: National Institute for Health and Care Excellence (NICE); 2022 Jun.

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