Table 14Summary of Liver Weights and Liver-Weight-to-Body-Weight Ratios for Female B6C3F1/N Mice in the Two-week Gavage Study of Trans-resveratrola,b

0
mg/kg/day		156
mg/kg/day		312
mg/kg/day		625
mg/kg/day		1,250
mg/kg/day		2,500
mg/kg/day
n 555555
Female
Necropsy Body Wt. (g)19.9 ± 0.219.5 ± 0.420.1 ± 0.520.3 ± 0.419.6 ± 0.519.6 ± 0.4
Liver
   Absolute (g)1.19 ± 0.051.16 ± 0.041.18 ± 0.041.22 ± 0.031.19 ± 0.041.30 ± 0.05
   Relative (mg/g)c59.95 ± 2.07**59.39 ± 0.6558.76 ± 1.4260.42 ± 0.9060.64 ± 1.1666.21 ± 1.78**

Statistical significance for a dose group indicates a significant pairwise test compared to the vehicle control group. Statistical significance for the vehicle control group indicates a significant trend test.

**

Statistically significant at p ≤ 0.01.

a

Data are presented as mean ± standard error.

b

Statistical analysis performed by the Jonckheere (trend) and Williams or Dunnett (pairwise) tests.

c

Relative organ weights (organ-weight-to-body-weight ratios) are given as mg organ weight/g body weight.

From: Results

Cover of NTP Technical Report on the Toxicity Studies of Trans-resveratrol (CASRN 501-36-0) Administered by Gavage for Two Weeks or Three Months to F344/NTac Rats, Wistar Han [Crl:WI(Han)] Rats, and B6C3F1/N Mice
NTP Technical Report on the Toxicity Studies of Trans-resveratrol (CASRN 501-36-0) Administered by Gavage for Two Weeks or Three Months to F344/NTac Rats, Wistar Han [Crl:WI(Han)] Rats, and B6C3F1/N Mice: Toxicity Report 102 [Internet].
National Toxicology Program.
Research Triangle Park (NC): National Toxicology Program; 2021 Dec.
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