Table 1, Overview of Map Characteristics - Drugs and Devices for Migraine Prevention: Interactive Evidence Maps

	Key Question 1	Key Question 2
	Map 1. Benefits and Harms of Selected Interventions for Migraine Prevention: Evidence from Placebo/Sham-Controlled RCTs	Map 2. What Types of Drugs and Devices have Been Studied with RCTs for Migraine Prevention?	Map 3. Head-to-Head Comparisons of Drugs and Devices for Prevention
Type of RCTs	Placebo/Sham Controlled	Placebo/Sham Controlled	Head-to-Head Comparisons
Criteria for interventions to be displayed in map	All interventions of interest displayed (including those for which no placebo-/sham-controlled RCTs were identified)	Only interventions assessed with placebo-/sham-controlled RCTs displayed	Only interventions assessed with head-to-head RCTs displayed
Summarizes Efficacy	Yes	No	No
Key Information Reported	For each individual intervention, pooled analysis of the following:: Migraine reduction (migraine days per month) Trial dropout due to adverse events Adverse events	Number of trials and number of patients randomized displayed by the following: Type of intervention (i.e. drug class) Individual drugs or devices Number of existing head-to-head comparisons for individual drugs or devices	Number of head-to-head comparisons (including dose comparisons) for individual drugs and devices Study details for each comparison, including author, migraine type, and comparison arms (intervention and subjects per arm)

Key Question 1

Key Question 2

Map 1. Benefits and Harms of Selected Interventions for Migraine Prevention: Evidence from Placebo/Sham-Controlled RCTs

Map 2. What Types of Drugs and Devices have Been Studied with RCTs for Migraine Prevention?

Map 3. Head-to-Head Comparisons of Drugs and Devices for Prevention

Type of RCTs

Placebo/Sham Controlled

Head-to-Head Comparisons

Criteria for interventions to be displayed in map

All interventions of interest displayed (including those for which no placebo-/sham-controlled RCTs were identified)

Only interventions assessed with placebo-/sham-controlled RCTs displayed

Only interventions assessed with head-to-head RCTs displayed

Summarizes Efficacy

Yes

Key Information Reported

For each individual intervention, pooled analysis of the following::

Number of trials and number of patients randomized displayed by the following:

Number of existing head-to-head comparisons for individual drugs or devices

Number of head-to-head comparisons (including dose comparisons) for individual drugs and devices

Study details for each comparison, including author, migraine type, and comparison arms (intervention and subjects per arm)

Drugs and Devices for Migraine Prevention: Interactive Evidence Maps [Internet].

Tsou AY, Rouse B, Bloschichak A, et al.

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