TABLE 25

The EVPPI for parameters from PROPELS trial

Parameter groupPer-person EVPPI (£)Whole population (n = 100,000 per annum)aNon-South Asian population (n = 94,700 per annum)South Asian population (n = 5300 per annum)
EVPPI for the UK over 10 years (£M)Per-person EVPPI (£)EVPPI for the UK over 10 years (£M)Per-person EVPPI (£)EVPPI for the UK over 10 years (£M)
Total EVPI280279.6298.90283.1182.809.7
HbA1c overall162161.6193.25183.089.374.7
HbA1c at 12 months36136.1149.46141.568.193.6
HbA1c at 48 months154153.6180.43170.946.342.5
T2D diagnoses overall161161.1159.82151.351.102.7
T2D diagnoses at 12 months111110.7123.26116.74.240.2
T2D diagnoses at 48 months5252.055.7152.815.440.8
Step count overall135135.1167.32158.571.083.8
Step count at 12 months9595.0145.04137.462.583.3
Step count at 48 months121120.6126.57119.941.532.2
a

Note that the EVPI values were estimated in using weighted results for each PSA run. For example, whole-population QALYs in PSA run 1 = (947,000 * QALYs in the non-South Asian population in PSA run 1 + 5300 * QALYs in the South Asian population in PSA run 1)/100,000. As such, the results may not match the weighted average of the results in the two population subgroups.

From: Chapter 6, Cost-effectiveness analysis

Cover of Behavioural interventions to promote physical activity in a multiethnic population at high risk of diabetes: PROPELS three-arm RCT
Behavioural interventions to promote physical activity in a multiethnic population at high risk of diabetes: PROPELS three-arm RCT.
Health Technology Assessment, No. 25.77.
Khunti K, Griffin S, Brennan A, et al.
Southampton (UK): NIHR Journals Library; 2021 Dec.
Copyright © 2021 Khunti et al. This work was produced by Khunti et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.

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