|
Machine usage (hours/night)
Follow-up 4 to 52 weeks
|
268
(4 studies)
|
⊕⊕⊝⊝
LOW11,
due to risk of bias,
| | control group risk not available4 |
The mean machine usage (hours/night) in the intervention groups was
0.14 higher
(0.17 lower to 0.45 higher)
|
|
Symptoms (Epworth Sleepiness Scale)
Scale from 0-24
Higher is worse
Follow-up 4 to 12 weeks
|
226
(4 studies)
|
⊕⊝⊝⊝
LOW11,
due to risk of bias,
| | control group risk not available4 |
The mean symptoms (epworth sleepiness scale) in the intervention groups was
0.49 lower
(1.46 lower to 0.48 higher)
|
|
Withdrawals (parallel group trials/first arm cross-over trials)
Follow-up 4 to 52 weeks
|
261
(3 studies)
|
⊕⊝⊝⊝
VERY LOW11,2
due to risk of bias, imprecision
|
RR 0.61
(0.33 to 1.15)
| Moderate |
| 138 per 1000 |
54 fewer per 1000
(from 92 fewer to 21 more)
|
|
Quality of life (Functional Outcome of Sleep Questionnaire)
Scale from 5-20
higher is better
Follow-up 8 weeks
|
151
(1 study)
|
⊕⊕⊝⊝
LOW11,2
due to risk of bias, imprecision
| |
Mean in control group was
5.1
|
The mean quality of life (functional outcome of sleep questionnaire) in the intervention groups was
0.8 lower
(6.08 lower to 4.48 higher)
|
|
Quality of life (Sleep Association Quality of Life Index)
Scale 1-7
Higher is better
|
28
(1 study)
|
⊕⊕⊕⊝
MODERATE1
due to risk of bias
| | control group risk not available4 |
The mean quality of life (sleep association quality of life index) in the intervention groups was
0.4 higher
(0.34 lower to 1.14 higher)
|
|
Quality of life (SF-36 questionnaire) - Physical health
Scale from 0-100
Higher is better
|
151
(1 study)
|
⊕⊝⊝⊝
VERY LOW1,2
due to risk of bias, imprecision
| |
Mean in control group was
1.2
|
The mean quality of life (sf-36 questionnaire) - physical health in the intervention groups was
0.6 higher
(2.21 lower to 3.41 higher)
|
|
Quality of life (SF-36 questionnaire) - Mental heath
Scale from 0-100
Higher is better
|
151
(1 study)
|
⊕⊕⊝⊝
LOW11,2
due to risk of bias, imprecision
| |
Mean in control group was
4.6
|
The mean quality of life (sf-36 questionnaire) - mental health in the intervention groups was
2.9 lower
(7.09 lower to 1.29 higher)
|
|
Apnoea Hypopnoea Index (events/hr)
Lower is better
Follow-up 4 to 8weeks
|
179
(2 studies)
|
⊕⊝⊝⊝
VERY LOW1,2
due to risk of bias, imprecision
| |
The mean AHI was
6.6 events/hour
|
The mean apnoea hypopnoea index (events/hr) in the intervention groups was
1.36 higher
(6.92 lower to 9.63 higher)
|
| Patient preference - BiPAP/no preference or CPAP |
88
(2 studies)
|
⊕⊝⊝⊝
VERY LOW1,2,3
due to risk of bias, inconsistency, imprecision
|
RR 0.88
(0.47 to 1.65)
| Moderate |
| 545 per 1000 |
65 fewer per 1000
(from 289 fewer to 354 more)
|
|
Tolerability outcomes - Dry mouth
Follow-up 4 to 52 weeks
|
151
(1 study)
|
⊕⊝⊝⊝
VERY LOW1,2
due to risk of bias, imprecision
|
RR 0.56
(0.15 to 2.17)
| Moderate |
| 75 per 1000 |
33 fewer per 1000
(from 64 fewer to 88 more)
|
|
Tolerability outcomes - Mask intolerance
Follow-up 4 to 52 weeks
|
151
(1 study)
|
⊕⊝⊝⊝
VERY LOW1,2
due to risk of bias, imprecision
|
RR 1.13
(0.45 to 2.85)
| Moderate |
| 100 per 1000 |
13 more per 1000
(from 55 fewer to 185 more)
|
|
Treatment comfort score
0-100 VAS
Follow-up 4 to 52 weeks
|
28
(1 study)
|
⊕⊕⊝⊝
LOW1,2
due to risk of bias
| | control group risk not available4 |
The mean treatment comfort score in the intervention groups was
9 higher
(3.54 lower to 21.54 higher)
|
