TABLE 4-1, Cause-Specific Mortality (deaths per 100,000 population), 1990–1993 and 2015–2017: Non-Hispanic White Adults Ages 25–64 - High and Rising Mortality Rates Among Working-Age Adults

Warning: The NCBI web site requires JavaScript to function. more...

TABLE 4-1Cause-Specific Mortality (deaths per 100,000 population), 1990–1993 and 2015–2017: Non-Hispanic White Adults Ages 25–64

Age Group	Non-Hispanic White Males
Age Group	25–44				45–54				55–64
All-Cause Mortality Rate 1990–1993	212.29				520.80				1345.21
All-Cause Mortality Rate 2015–2017	222.62				493.39				1085.81
Change 1990–1993 to 2015–2017	10.33				–27.41				–259.40
(Change as % of 1990–1993 mortality)	4.87				–5.26				–19.28
Cause of Death	Mortality Rate		Change		Mortality Rate		Change		Mortality Rate		Change
Cause of Death	1990–1993	2015–2017	Abs Chg	% of Total +/– Chg	1990–1993	2015–2017	Abs Chg	% of Total +/– Chg	1990–1993	2015–2017	Abs Chg	% of Total +/– Chg
Infectious and Parasitic Diseases
HIV/AIDS	35.83	1.05	–34.78	–56.7	25.76	3.81	–21.95	–15.4	10.16	3.49	–6.67	–1.6
Non-HIV/AIDS	3.62	2.57	–1.05	–1.7	6.54	11.03	4.49	3.9	13.68	29.26	15.59	9.5
Cancers
Liver Cancer	0.49	0.52	0.03	0.0	2.54	5.03	2.50	2.2	8.75	25.79	17.04	10.3
Lung Cancer	4.34	1.61	–2.73	–4.5	52.60	21.22	–31.37	–22.0	198.91	90.90	–108.02	–25.5
All Other Cancers	20.90	15.55	–5.35	–8.7	91.52	70.23	–21.29	–14.9	271.79	206.16	–65.63	–15.5
Cardio and Metabolic Diseases
Endocrine, Nutritional, & Metabolic	5.12	7.00	1.88	2.6	14.95	24.93	9.97	8.6	36.03	56.26	20.23	12.3
Hypertensive Heart Disease	1.08	3.86	2.78	3.9	5.61	16.00	10.39	9.0	15.20	32.61	17.40	10.6
Ischemic & Other Circulatory System	30.76	24.52	–6.25	–10.2	177.57	110.92	–66.65	–46.7	517.49	279.65	–237.84	–56.1
Substance Use and Mental Health
Drug Poisoning	9.55	62.43	52.88	73.7	4.39	47.73	43.34	37.6	2.58	31.42	28.84	17.5
Alcohol-Induced^{^*}	4.81	6.70	1.89	2.6	13.33	21.83	8.50	7.4	20.73	31.58	10.85	6.6
Suicide	23.09	32.30	9.21	12.8	22.36	35.21	12.85	11.1	24.75	32.79	8.03	4.9
Mental & Behavioral Disorders	3.84	5.10	1.26	1.8	7.35	12.69	5.34	4.6	11.37	21.01	9.64	5.9
Other Body System Diseases
Nervous System	3.11	4.63	1.53	2.1	7.01	11.98	4.98	4.3	15.71	28.44	12.74	7.7
Genitourinary System	1.01	1.29	0.28	0.4	3.18	5.62	2.44	2.1	10.42	16.02	5.59	3.4
Respiratory System	4.49	4.23	–0.27	–0.4	18.32	20.26	1.94	1.7	85.70	81.10	–4.60	–1.1
Digestive System^{^*}	5.50	4.59	–0.91	–1.5	17.23	19.94	2.72	2.4	39.05	44.79	5.74	3.5
Other Causes of Death
Homicide	8.12	5.66	–2.46	–4.0	6.26	4.78	–1.48	–1.0	4.76	3.42	–1.34	–0.3
Transport Accidents	27.21	22.22	–4.99	–8.1	20.37	22.13	1.77	1.5	20.00	23.30	3.30	2.0
Other External Causes of Death	12.69	10.43	–2.26	–3.7	14.19	15.99	1.80	1.6	19.63	25.58	5.95	3.6
All Other Causes of Death	6.72	6.38	–0.34	–0.6	9.74	12.04	2.31	2.0	18.49	22.24	3.76	2.3
Total Change: Increase (+)	71.74				15.33				164.70
Total Change: Decrease (–)	–61.40				–42.74				–424.09
Age Group	Non-Hispanic White Females
Age Group	25–44				45–54				55–64
All-Cause Mortality Rate 1990–1993	88.93				295.15				767.20
All-Cause Mortality Rate 2015–2017	121.90				314.97				659.91
Change 1990–1993 to 2015–2017	32.97				19.82				–107.29
(Change as % of 1990–1993 mortality)	37.07				6.72				–13.98
Cause of Death	Mortality Rate		Change		Mortality Rate		Change		Mortality Rate		Change
Cause of Death	1990–1993	2015–2017	Abs Chg	% of Total +/– Chg	1990–1993	2015–2017	Abs Chg	% of Total +/– Chg	1990–1993	2015–2017	Abs Chg	% of Total +/– Chg
Infectious and Parasitic Diseases
HIV/AIDS	2.09	0.37	–1.72	–13.3	1.07	0.71	–0.36	–0.6	0.67	0.58	–0.08	0.0
Non-HIV/AIDS	1.43	2.41	0.98	2.1	3.79	8.45	4.66	5.8	9.40	19.68	10.28	11.0
Cancers
Liver Cancer	0.24	0.39	0.14	0.3	1.37	2.14	0.77	1.0	3.79	7.52	3.74	4.0
Lung Cancer	3.07	1.48	–1.59	–12.3	33.42	19.34	–14.08	–23.1	104.57	67.85	–36.72	–18.3
All Other Cancers	26.62	19.19	–7.43	–57.6	111.06	76.40	–34.67	–57.0	248.27	173.33	–74.95	–37.3
Cardio and Metabolic Diseases
Endocrine, Nutritional, & Metabolic	3.06	4.92	1.86	4.0	10.04	14.76	4.72	5.9	28.45	32.24	3.78	4.0
Hypertensive Heart Disease	0.33	1.65	1.32	2.9	2.34	7.30	4.96	6.1	7.93	15.27	7.34	7.8
Ischemic & Other Circulatory System	11.88	13.09	1.21	2.6	60.58	49.74	–10.84	–17.8	207.31	120.51	–86.80	–43.2
Substance Use and Mental Health
Drug Poisoning	4.10	30.36	26.26	57.2	4.14	33.26	29.12	36.1	3.45	22.56	19.12	20.4
Alcohol-Induced^{^*}	1.71	3.83	2.12	4.6	4.21	11.73	7.52	9.3	6.52	12.65	6.13	6.5
Suicide	4.64	7.85	3.21	7.0	5.48	9.10	3.62	4.5	5.16	7.59	2.44	2.6
Mental & Behavioral Disorders	1.24	3.08	1.84	4.0	2.25	5.92	3.67	4.5	3.81	8.86	5.06	5.4
Other Body System Diseases
Nervous System	2.28	3.53	1.25	2.7	6.03	9.70	3.68	4.6	12.82	24.01	11.20	12.0
Genitourinary System	0.71	1.18	0.47	1.0	2.54	4.51	1.97	2.4	7.80	12.16	4.37	4.7
Respiratory System	3.03	4.18	1.15	2.5	14.45	20.87	6.41	7.9	60.25	68.84	8.58	9.2
Digestive System^{^*}	2.68	3.75	1.06	2.3	9.47	13.70	4.22	5.2	24.41	29.13	4.72	5.0
Other Causes of Death
Homicide	3.36	2.59	–0.77	–5.9	2.48	2.10	–0.38	–0.6	1.72	1.57	–0.16	–0.1
Transport Accidents	9.60	8.22	–1.39	–10.7	8.54	8.04	–0.51	–0.8	9.29	7.12	–2.17	–1.1
Other External Causes of Death	2.59	3.49	0.89	1.9	4.15	6.64	2.49	3.1	6.97	11.29	4.32	4.6
All Other Causes of Death	4.26	6.38	2.12	4.6	7.70	10.55	2.85	3.5	14.62	17.14	2.52	2.7
Total Change: Increase (+)	45.87				80.66				93.59
Total Change: Decrease (–)	–12.90				–60.83				–200.88

*: Changes in the International Classification of Diseases (ICD)-10 code for diseases of the digestive system in 2006 affected the comparability of both digestive system deaths and alcohol-induced deaths before and after that year. More information is provided in Chapter 5.
: NOTE: The top 3 causes of death for each age group in each period are highlighted in bolded red text.
: Light orange highlights indicate an absolute increase in the overall mortality rate of ≥5 deaths/100,000 population.
: Dark orange highlights indicate that a cause of death is responsible for ≥10 percent of the total increase in mortality.
: Light green highlights indicate an absolute decrease in the overall mortality rate of ≥5 deaths/100,000 population.
: Dark green highlights indicate that a cause of death is responsible for ≥10 percent of the total decrease in mortality.
: The table shows mortality rates and change in all-cause and cause-specific mortality rates among non-Hispanic White working-age adults by age group (25–44, 45–54, and 55–64) for males (upper table) and females (lower table). Changes in mortality are presented as both the absolute change in mortality rates and the percentage of the total increase (or decrease) in mortality. Mortality rates within each age group are age-adjusted by single-year of age to match the age distribution of the U.S. population in 2000 in order to improve comparability over time. These causes of death are exhaustive of all underlying cause-of-death codes and are based on the ICD-9 (1990–1998) and ICD-10 (1999–2017) codes. More information about the classification of causes of death can be found in Chapter 5.
: SOURCE: Data from https://www.cdc.gov/nchs/nvss/nvss-restricted-data.htm.

From: 4, U.S. Trends in Cause-Specific Mortality Among Working-Age Adults

High and Rising Mortality Rates Among Working-Age Adults.

National Academies of Sciences, Engineering, and Medicine; Division of Behavioral and Social Sciences and Education; Committee on National Statistics; Committee on Population; Committee on Rising Midlife Mortality Rates and Socioeconomic Disparities; Becker T, Majmundar MK, Harris KM, editors.

Washington (DC): National Academies Press (US); 2021 Mar 2.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.