| QC tool | Analyte type | Sample type | QC scope | Applicability grade | Accessibility grade | Delay Consequence | Reference |
|---|---|---|---|---|---|---|---|
| Transferrin receptor | Protein | Serum | Pre-centrifugation delay | 1 | 1 | 8 h blood pre-centrifugation delay 90% increase | De Jongh et al. (1997) |
| K+ | Ion | Serum | Pre-centrifugation delay at 4 °C | 1 | 1 | 1 day pre-centrifugation delay at 4 °C 200% increase 7 day pre-centrifugation delay at 4 °C 500% increase | Heins et al. (1995) |
| GM-CSF, IL-1α, G-CSF | Protein | EDTA plasma ± PI | Pre-centrifugation delay | 1 | 1 | 2 h pre-centrifugation delay at RT 11–20-fold increase without PI 7–10-fold increase with PI | Ayache et al. (2006) |
| sCD40L | Protein | Serum | Exposure to RT | 1 | 1 | 12 h at 37 °C or 48 h at RT Complete degradation | Lengellé et al. (2008) |
| Vitamin E | Vitamin | EDTA plasma | Storage conditions | 1 | 1 | > 24 months at −20 °C > 90% decrease | Ockè et al. (1995) |
| MMP-7 | Protein | Serum | Freeze-thawing | 1 | 1 | 30 freeze–thaw cycles Loss of MMP-7 | Chaigneau et al. (2007) |
| DUSP1 expression | RNA | Fresh prostatic tissue | Warm ischaemia time | 1 | 1 | Warm ischaemia 14-fold upregulation | Lin et al. (2006) |
| p-Tyr, ERBB2 (alias HER2; alias Neu)-Tyr1248, PTK2 (alias FAK) | Protein | Breast tissue | Cold ischaemia time | 1 | 1 | 24 h of cold ischaemia Complete denaturation of phosphorylated epitopes | De Cecco et al. (2009) |
±, with or without; EDTA, ethylenediaminetetraacetic acid; G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-1α, interleukin 1 alpha; K+, potassium; MMP-7, matrix metalloproteinase-7; PI, protease inhibitors; QC, quality control; RT, room temperature; Tyr, tyrosine.
Source: Adapted from Betsou et al. (2013), Copyright (2013), with permission from Elsevier.
From: SECTION 3., Recommendations for biobanks
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