PubChem BioAssay Table

AIDAssay NameAssay TypeTargetPowder SampleCompounds
1321Primary Cell-based HTS Assay for Inhibitors of Wee1 DegradationPrimary Assay (1X %INH)Wee1No5 μM
1410Confirmation cell-based HTS assay for inhibitors of Wee1 degradationConfirmation Assay (3X %INH)Wee1No5 μM
1412Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation.Dose Response (3X EC50)Wee1No10-point, 1:3 dilution starting at 50 μM
1413Cytotoxicity counterscreen assay for inhibitors of Wee1 degradation.Dose Response Counterscreen Assay (3X CC50)CytotoxicityNo10-point, 1:3 dilution starting at 50 μM
1414Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradationDose Response Counterscreen (3X% EC50)Cyclin BNo10-point, 1:3 dilution starting at 50 μM
1807Summary of probe development efforts to identify inhibitors of Wee1 degradationSummaryWee1N/AN/A
2088Late stage results from the probe development effort to identify inhibitors of Wee1 degradationLate StageWee1YesVarious

From: Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.