CID/ML#Target NameEC50 (nM) [SID, AID]Anti- target NameEC50 (μM) [SID, AID]Fold SelectiveSecondary Assay(s) Name: IC50/EC50 (nM) [SID, AID]
CID-3237904/ML118 (powder CID-44552613)Wee1 Degradation7.87 μM [SID-4243143 AID-1412] (powder SID-87235992)Cyclin B>49.75 μM [SID SID-4243143 AID-1414]>6.3Cytotoxicity Assay: >49.75 μM [SID-4243143, AID-1413]

G2/M Arrest Assay: Active [TFA salt, powder SID-87235992/CID-44552613, AID-2088]

From: Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.