RECOMMENDATIONS

Monitoring of Patients Taking RBV

  • While patients are taking RBV, clinicians should perform hemoglobin testing at weeks 2 and 4 of treatment and every 4 weeks thereafter until therapy is complete. (A1)

Monitoring for HBV Reactivation

  • In patients who are HBsAg-positive and have no detectable HBV DNA, clinicians should monitor for HBV reactivation by performing AST, ALT, and HBV DNA tests every 4 weeks during HCV treatment. (A3)
  • Clinicians new to HCV treatment should consult a liver disease or experienced viral hepatitis specialist for further evaluation of patients who develop detectable HBV DNA. (A3)

Abbreviations: ALT, alanine transaminase; AST, aspartate aminotransferase; HBsAg, HBV surface antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; RBV, ribavirin.

From: Treatment of Chronic Hepatitis C Virus Infection in Adults

Cover of Treatment of Chronic Hepatitis C Virus Infection in Adults
Treatment of Chronic Hepatitis C Virus Infection in Adults [Internet].
Bernstein DE, Aron JS, Kerr CA, et al.
Baltimore (MD): Johns Hopkins University; 2023 Apr.
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