Table 10Quality assessment of expert evidence – redacted outcomes (as yet unpublished)

Quality assessmentNo of patientsEffectQualityImportance
No of studiesDesignRisk of biasInconsistencyIndirectnessImprecisionOther considerationsStenting + planned bowel resection or palliative careEmergency bowel surgeryRelative (95% CI)Absolute
30-day mortality - Curative intent
1randomised trialsno serious risk of bias1no serious inconsistencyno serious indirectnessserious2none[REDACTED TEXT][REDACTED TEXT][REDACTED TEXT][REDACTED TEXT]MODERATECRITICAL
3-year overall survival, event is death from any cause - Curative intent
1randomised trialsno serious risk of bias1no serious inconsistencyno serious indirectnessserious2none[REDACTED TEXT][REDACTED TEXT][REDACTED TEXT][REDACTED TEXT]MODERATEIMPORTANT
Hospital stay (time to event analysis of leaving hospital)- Curative intent
1randomised trialsno serious risk of bias1no serious inconsistencyno serious indirectnessserious2none[REDACTED TEXT][REDACTED TEXT][REDACTED TEXT][REDACTED TEXT]MODERATEIMPORTANT
Hospital stay - Palliative intent
1randomised trialsno serious risk of bias1no serious inconsistencyno serious indirectnessserious2none[REDACTED TEXT][REDACTED TEXT][REDACTED TEXT][REDACTED TEXT]MODERATEIMPORTANT

CI: confidence interval; HR: hazard ratio; RR: relative risk

1

Risk of bias assessed using trial protocol

2

Quality of evidence downgraded by 1 because of imprecision of the effect estimate (< 300 events for dichotomous outcomes or < 400 patients for continuous outcomes)

3

Numbers of events or participants were not reported

From: Effectiveness of stenting for acute large bowel obstruction

Cover of Effectiveness of stenting for acute large bowel obstruction
Effectiveness of stenting for acute large bowel obstruction: Colorectal cancer (update): Evidence review C9.
NICE Guideline, No. 151.
National Guideline Alliance (UK).
Copyright © NICE 2020.

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