From: Effectiveness of stenting for acute large bowel obstruction
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National Guideline Alliance (UK). Effectiveness of stenting for acute large bowel obstruction: Colorectal cancer (update): Evidence review C9. London: National Institute for Health and Care Excellence (NICE); 2020 Jan. (NICE Guideline, No. 151.)
Effectiveness of stenting for acute large bowel obstruction: Colorectal cancer (update): Evidence review C9.
Show detailsTable 10Quality assessment of expert evidence – redacted outcomes (as yet unpublished)
| Quality assessment | No of patients | Effect | Quality | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Stenting + planned bowel resection or palliative care | Emergency bowel surgery | Relative (95% CI) | Absolute | ||
| 30-day mortality - Curative intent | ||||||||||||
| 1 | randomised trials | no serious risk of bias1 | no serious inconsistency | no serious indirectness | serious2 | none | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | MODERATE | CRITICAL |
| 3-year overall survival, event is death from any cause - Curative intent | ||||||||||||
| 1 | randomised trials | no serious risk of bias1 | no serious inconsistency | no serious indirectness | serious2 | none | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | MODERATE | IMPORTANT |
| Hospital stay (time to event analysis of leaving hospital)- Curative intent | ||||||||||||
| 1 | randomised trials | no serious risk of bias1 | no serious inconsistency | no serious indirectness | serious2 | none | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | MODERATE | IMPORTANT |
| Hospital stay - Palliative intent | ||||||||||||
| 1 | randomised trials | no serious risk of bias1 | no serious inconsistency | no serious indirectness | serious2 | none | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | [REDACTED TEXT] | MODERATE | IMPORTANT |
CI: confidence interval; HR: hazard ratio; RR: relative risk
- 1
Risk of bias assessed using trial protocol
- 2
Quality of evidence downgraded by 1 because of imprecision of the effect estimate (< 300 events for dichotomous outcomes or < 400 patients for continuous outcomes)
- 3
Numbers of events or participants were not reported
- Colonic stent placement as a bridge to surgery in patients with left-sided malignant large bowel obstruction. An observational study.[G Chir. 2014]Colonic stent placement as a bridge to surgery in patients with left-sided malignant large bowel obstruction. An observational study.Occhionorelli S, Tartarini D, Cappellari L, Stano R, Vasquez G. G Chir. 2014 Nov-Dec; 35(11-12):283-9.
- Review Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: a systematic review and meta-analysis.[Surg Oncol. 2013]Review Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: a systematic review and meta-analysis.Cirocchi R, Farinella E, Trastulli S, Desiderio J, Listorti C, Boselli C, Parisi A, Noya G, Sagar J. Surg Oncol. 2013 Mar; 22(1):14-21. Epub 2012 Nov 24.
- Colonic stenting as a bridge to surgery in malignant large-bowel obstruction: a report from two large multinational registries.[Am J Gastroenterol. 2011]Colonic stenting as a bridge to surgery in malignant large-bowel obstruction: a report from two large multinational registries.Jiménez-Pérez J, Casellas J, García-Cano J, Vandervoort J, García-Escribano OR, Barcenilla J, Delgado AA, Goldberg P, Gonzalez-Huix F, Vázquez-Astray E, et al. Am J Gastroenterol. 2011 Dec; 106(12):2174-80. Epub 2011 Nov 15.
- Colonic stenting as bridge to surgery versus emergency surgery for management of acute left-sided malignant colonic obstruction: a multicenter randomized trial (Stent-in 2 study).[BMC Surg. 2007]Colonic stenting as bridge to surgery versus emergency surgery for management of acute left-sided malignant colonic obstruction: a multicenter randomized trial (Stent-in 2 study).van Hooft JE, Bemelman WA, Breumelhof R, Siersema PD, Kruyt PM, van der Linde K, Veenendaal RA, Verhulst ML, Marinelli AW, Gerritsen JJ, et al. BMC Surg. 2007 Jul 3; 7:12. Epub 2007 Jul 3.
- Review Colonic Stenting in the Emergency Setting.[Medicina (Kaunas). 2021]Review Colonic Stenting in the Emergency Setting.Morino M, Arezzo A, Farnesi F, Forcignanò E. Medicina (Kaunas). 2021 Apr 1; 57(4). Epub 2021 Apr 1.
- Table 10, Quality assessment of expert evidence – redacted outcomes (as yet unpu...Table 10, Quality assessment of expert evidence – redacted outcomes (as yet unpublished) - Effectiveness of stenting for acute large bowel obstruction
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