Table 41.1

Risk factors for GF

Pre-transplant difficult to modifyPre-transplant easy to modifyPeri-post transplant
HLA mismatches
Nonmalignant disease
Advanced disease
Extensive marrow fibrosis extensive prior treatment
Donor age
Splenomegaly		Graft source
Conditioning
T-cell depletion		CD34+ cell count
Viral infections
GVHD
Drug toxicity
Iron overload
HLA antibodies
Transfusion history

From: Chapter 41, Graft Failure

Cover of The EBMT Handbook
The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]. 7th edition.
Carreras E, Dufour C, Mohty M, et al., editors.
Cham (CH): Springer; 2019.
Copyright 2019, EBMT and the Author(s)

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