Table 36Leeds Videographic Gait Assessment for Study 701 — APT Population

AboBoNTA

(N = 52)

Placebo

(N = 52)

Initial Foot Contact
Week 4, N (%)
 Heel strike▬▬
 Flat foot▬▬
 Toe strike▬▬
 Mild toe▬▬
 Marked toe▬▬
 P value▬
Week 16, N (%)
 Heel strike▬▬
 Flat foot▬▬
 Toe strike▬▬
 Mild toe▬▬
 Marked toe▬▬
 P value▬
Leeds Videographic Assessment
At week 4
Degree of knee flexion,a N (%)
 Neutral/slightly flexed▬▬
 Hyperextended▬▬
 Marked knee flexion▬▬
 P value▬
Rocker-bottom foot,a N (%)
 Not present▬▬
 Present▬▬
 P value▬
Hindfoot deformity,a N (%)
 Neutral▬▬
 Occasionally neutral▬▬
 Valgus▬▬
 Varus▬▬
 P value▬
Use of walking aids,b N (%)▬▬
At week 16
Degree of knee flexion,a N (%)
 Neutral/slightly flexed▬▬
 Hyperextended▬▬
 Marked knee flexion▬▬
 P value▬
Rocker-bottom foot,a N (%)▬▬
 Not present▬▬
 Present▬▬
 P value▬
Hindfoot deformity,a N (%)▬▬
 Neutral▬▬
 Occasionally neutral▬▬
 Valgus▬▬
 Varus▬▬
 P value▬
Use of walking aids,b N (%)▬▬

aboBoNTA = abobotulinumtoxinA; APT = all patients treated; GMFM = Gross Motor Function Measure.

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Source: Study 701 Clinical Study Report.30

From: Appendix 4, Detailed Outcome Data

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Clinical Review Report: abobotulinumtoxinA (Dysport Therapeutic): (Ipsen Biopharmaceuticals Canada Inc.): Indication: For the symptomatic treatment of lower-limb spasticity in pediatric patients 2 years of age and older [Internet].
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