TABLE 3

Patient characteristics by year

YearOST patientsAge (years)Gender (% male)Medications (% of patients)
MBDBDZDPG
1998116032.7868.1086.038.4515.0042.0710.780.60
1999170732.4367.7285.827.7915.3537.2612.710.64
2000194833.0468.8483.2110.2217.3037.4713.860.87
2001235733.4368.2277.9418.2417.9535.5112.130.93
2002280533.9067.4573.1623.7816.5136.7213.581.21
2003327434.1667.7871.9027.0912.9834.1812.161.56
2004357434.5767.0469.5630.6411.5832.1811.392.52
2005378335.2666.9368.8932.3011.1032.8812.002.88
2006397836.2568.0069.4331.5710.4133.4313.703.14
2007411837.2167.5369.3130.6710.1332.2512.944.15
2008427637.9567.4571.0229.099.1032.1612.044.07
2009418838.6066.5272.1127.728.5531.4512.304.75
2010412939.4267.3573.1226.648.0930.3512.626.32
2011391940.1667.4473.0325.857.7630.6212.787.76
2012368140.8267.2470.9927.687.2530.0512.669.07
2013341341.4767.0769.3229.627.4728.6611.1011.08
2014267042.5567.4567.5730.827.6826.8910.9012.70
Overall12,78036.0466.6378.6236.0315.3747.4425.379.20
Trenda0.6810.9970.9711.0360.9300.9710.9951.213
SE (trend)0.00990.00210.00230.00250.00320.00210.00300.0058
p-value< 0.00010.2119< 0.0001< 0.0001< 0.0001< 0.00010.1149< 0.0001
Deviation< 0.00010.9956< 0.0001< 0.0001< 0.00010.07900.00700.3984

B, buprenorphine; BD, benzodiazepines; D, dihydrocodeine; M, methadone; PG, pregabalin/gabapentin; SE, standard error; ZD, z-drugs.

a

Trend is additive for age and multiplicative for all other outcomes.

Note

The totals of the percentages exceed 100% as a result of some patients being prescribed multiple medications within any given year.

From: Chapter 4, Trends in opiate substitution treatment, patient characteristics and prescribing practice

Cover of The impact of opiate substitution treatment on mortality risk in drug addicts: a natural experiment study
The impact of opiate substitution treatment on mortality risk in drug addicts: a natural experiment study.
Health Services and Delivery Research, No. 7.3.
Steer CD, Macleod J, Tilling K, et al.
Southampton (UK): NIHR Journals Library; 2019 Jan.
Copyright © Queen’s Printer and Controller of HMSO 2019. This work was produced by Steer et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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