Table 67Research recommendation statements

CriterionExplanation
PopulationChildren with cystic fibrosis, up to 6 years old (pre-school children)
Intervention
  • LCI, measure by multiple breath washout (MBW) testing at regular intervals
ComparatorsAlternative lung function test: FEV1 (measured by spirometry)
Outcomes
  • Change in lung function
  • Quality of life as measured by a validated tool, such as CF-QOL or CFQ-R)
  • Nutritional parameters (BMI, weight/height)
  • Time to chronic infection
  • Resource use
  • Unit costs
Study designRCT or cluster RCT
TimeframeWithin 2 years

From: 9, Pulmonary monitoring, assessment and management

Cover of Cystic Fibrosis
Cystic Fibrosis: Diagnosis and management.
NICE Guideline, No. 78.
National Guideline Alliance (UK).
Copyright © NICE 2017.

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