Table 53Annual probability of infection with intermittent pathogen

StudyIntermittent pathogenStrategy 1 (new) probabilityStrategy 2 (old) probability
Cohorts by pathogen
Federiksen 1999PA22.5%33.3%
France 2008BCC16.3%4.0%
Lee 2004PA34.5% (30%)a26.2% (28%)a
Whitford 1995bBCC2.1%9.0%
Protective equipment
Chen 2001BCC0.9%8.8%
Savant 2014cPA36%46%
Single inpatient room versus ward bed
Chen 2001BCC7.0%15.0%
France 2008BCC2.9%16.3%
Incomplete cohort segregation including en suite bathroom facilities versus no cohort segregation
Jones 2005dPA0.0%9.7%

BCC, B cepacia complex; PA, P aeruginosa

(a)

Prevalence data (incidence data) 1990 versus 2000

(b)

6 month probability translated into a 12 month probability using rates

(c)

Prevalence data as incidence data not calculable

(d)

2000 data compared to 2001 data as these are the dates when incidence is reported, the clinical evidence review compared 1999 to 2001 based on prevalence

From: Appendix K, Health Economics

Cover of Cystic Fibrosis
Cystic Fibrosis: Diagnosis and management.
NICE Guideline, No. 78.
National Guideline Alliance (UK).
Copyright © NICE 2017.

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