| Study | Prognostic indicator | Confounders adjusted for: | Effect size | Quality |
|---|---|---|---|---|
| Chen 2013 | GMFCS levels | Age - all participants aged mean 3.8 years and followed up for 6 months. | Language Standardised coefficient (β) =-0.22 p=<0.001 | Low |
| Parkes 2010 | CP subtype (bilateral versus unilateral), GMFCS level, ‘intellectual impairment’: severe = IQ <50, moderate = IQ 50 to 70, none = IQ >70. | CP subtype, GMFCS level, IQ (all participants assessed at 5 years). | Speech impairment Bilateral spastic CP versus unilateral spastic: OR 1.6 (95% CI: 1.1-2.4), p<0.001 Non-spastic CP versus unilateral spastic CP: OR 5.1 (95% CI: 2.8-9.1), p<0.001 GMFCS I (reference) GMFCS II: OR 2.1 (95% CI: 1.2-3.5) GMFCS III: OR 2.5 (95% CI: 1.3-4.9) GMFCS IV: OR 4.0 (95% CI: 1.9-8.4) GMFCS V: OR 8.0 (95% CI: 4.1-15.6) p< 0.001 IQ > 70 (reference) IQ 50-70: OR 2.7 (95% CI: 1.8-4.0) IQ < 50: OR 3.6 (95% CI: 1.8-4.0) p 0.001 | Moderate |
CP cerebral palsy, GMFCS Gross Motor Function Classification System, IQ intelligence quotient, OR odds ratio.
From: 10, Prognosis for walking, talking and life expectancy
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