Table 2Characteristics of Included Randomized Clinical Trial

First Author, Publication Year, CountryStudy DesignPatient CharacteristicsIntervention(s)Comparator(s)Clinical Outcomes
Kuffel, 2013, Germany16Double-blind crossoverIn-patients with major depressive disorder and age-and gender-matched healthy volunteer patients (n = 20 in each group)

Patients with common psychiatric comorbidities were excluded.
Single dose of clonidine hydrochloride 0.15 mgSingle dose of placeboMemory consolidation, memory retrieval, working memory with either neutral or negative valenced words

From: Clonidine for the Treatment of Psychiatric Conditions and Symptoms: A Review of Clinical Effectiveness, Safety, and Guidelines

Cover of Clonidine for the Treatment of Psychiatric Conditions and Symptoms: A Review of Clinical Effectiveness, Safety, and Guidelines
Clonidine for the Treatment of Psychiatric Conditions and Symptoms: A Review of Clinical Effectiveness, Safety, and Guidelines [Internet].
Chiu S, Campbell K.
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