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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

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Drugs and Lactation Database (LactMed®) [Internet].

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Zileuton

Last Revision: July 15, 2024.

Estimated reading time: 1 minute

CASRN: 111406-87-2

image 135016842 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

No published information is available on the use of zileuton during breastfeeding; however, manufacturer's data indicate that the dose in milk is low. An expert guideline considers that leukotriene receptor antagonists can be used during breastfeeding.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Bendien SA, de Kruif MD, Feitsma H, et al. Summary of the Dutch Multidisciplinary Practice Guideline on Asthma and Pregnancy. J Allergy Clin Immunol Pract 2024;12:1751-62 [PubMed: 38513758]

Substance Identification

Substance Name

Zileuton

CAS Registry Number

111406-87-2

Drug Class

Breast Feeding

Lactation

Milk, Human

Anti-Asthmatic Agents

Leukotriene Antagonists

Lipoxygenase Inhibitors

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Bookshelf ID: NBK501485PMID: 30000545

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