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Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Bookshelf ID: NBK501485PMID: 30000545
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 111406-87-2
Drug Levels and Effects
Summary of Use during Lactation
No published information is available on the use of zileuton during breastfeeding; however, manufacturer's data indicate that the dose in milk is low. An expert guideline considers that leukotriene receptor antagonists can be used during breastfeeding.[1]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Beclomethasone, Cromolyn, Montelukast, Terbutaline, Theophylline
References
- 1.
- Bendien SA, de Kruif MD, Feitsma H, et al. Summary of the Dutch Multidisciplinary Practice Guideline on Asthma and Pregnancy. J Allergy Clin Immunol Pract 2024;12:1751-62 [PubMed: 38513758]
Substance Identification
Substance Name
Zileuton
CAS Registry Number
111406-87-2
Drug Class
Breast Feeding
Lactation
Milk, Human
Anti-Asthmatic Agents
Leukotriene Antagonists
Lipoxygenase Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.