Table 7.Case-control studies on malignant lymphomas containing information on insecticide exposure

ReferenceLocationCancerNo. of exposed cases/controlsRelative risk95% CIComments
Hoar et al. (1986)Kansas, USANon-Hodgkin's lymphoma54/275
24/99
1.5
1.1
0.9–2.4
0.6–2.2
Insecticides; not adjusted for herbicide use
Adjusted for herbicide use; farmers only
Hoar Zahm et al. (1988)Kansas, USAHodgkin's disease38/275
32/214
25/132
0.8
0.9
1.1
0.5–1.4
0.5–1.5
0.6–1.9
Insecticide use
Insecticide use on animals
Insecticide use on crops
Unadjusted for other agricultural exposures
Hoar Zahm et al. (1990)Nebraska, USANon-Hodgkin's lymphoma104/321
NA
1.1
2.4
0.7–1.6
NA
Insecticides; not adjusted for herbicide use
Organophosphates; adjusted for 2, 4-D use
Risks rose with days per year of organo
phosphate insecticides after adjustment for herbicides
Woods et al. (1987); Woods & Polissar (1989)Washington, USANon-Hodgkin's lymphomaNA
NA
NA
NA
1.6
1.8
1.6
1.7
0.7–3.8
1.0–3.2
0.5–5.1
0.9–3.3
Chlordane
DDT
Chlordane for farmers only
DDT for farmers only
Not adjusted for other agricultural exposures
Persson et al. (1989)SwedenNon-Hodgkin's lymphoma0/3DDT exposure
Persson et al. (1989)SwedenHodgkin's disease3/37.50.8–70.0DDT, adjusted for some agricultural exposures; 90% CI
Hardell et al. (1981)SwedenMalignant lymphoma22/26


7/11
[1.8]


[1.6]
[1.0–3.2]


[0.6–4.1]
DDT, crude risk calculated from data in paper. Not adjusted for other agricultural exposures
Crude risk for DDT, without exposure to phenoxyacetic acid herbicides

NA, not available

From: Occupational exposures in spraying and application of insecticides

Cover of Occupational Exposures in Insecticide Application, and Some Pesticides
Occupational Exposures in Insecticide Application, and Some Pesticides.
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 53.
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.
©International Agency for Research on Cancer, 1991.

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