TABLE 26

Sensitivity analysis of varying the prevalence parameter in the prenatal model

StrategyPrevalence = 8.7%Prevalence = 12%
Total cost (£)Total QALYsProbability of being cost-effective at WTP ofTotal cost (£)Total QALYsProbability of being cost-effective at WTP of
£20,000£30,000£20,000£30,000
Whooley questions followed by EPDS (≥ 13-point cut-off point)43.300.336900.4200.31555.900.335140.5080.359
EPDS (≥ 13-point cut-off point) only46.600.336920.0300.03759.600.335170.0530.053
Whooley questions followed by PHQ-947.700.337070.5240.53363.400.335370.3990.428
Routine care case identification62.400.336970.0000.00075.100.335240.0010.001
Whooley questions followed by EPDS (≥ 10-point cut-off point)68.100.337240.0150.05986.400.335610.0230.071
EPDS (≥ 10-point cut-off point) only79.000.337290.0090.04297.700.335680.0140.063
Whooley questions only82.700.337310.0020.015101.700.335710.0040.026

Strategies with the highest probability of being cost-effective at different WTP thresholds are shaded.

From: Chapter 7, Cost-effectiveness of screening/case-finding strategies for perinatal depression

Cover of Identifying perinatal depression with case-finding instruments: a mixed-methods study (BaBY PaNDA – Born and Bred in Yorkshire PeriNatal Depression Diagnostic Accuracy)
Identifying perinatal depression with case-finding instruments: a mixed-methods study (BaBY PaNDA – Born and Bred in Yorkshire PeriNatal Depression Diagnostic Accuracy).
Health Services and Delivery Research, No. 6.6.
Littlewood E, Ali S, Dyson L, et al.
Southampton (UK): NIHR Journals Library; 2018 Feb.
Copyright © Queen’s Printer and Controller of HMSO 2018. This work was produced by Littlewood et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.