TABLE 25

Sensitivity, specificity and diagnostic outcomes of a hypothetical cohort of 1000 women screened for prenatal depression

Screening/case-finding strategyTPs per 1000 women screenedFPs per 1000 women screenedTNs per 1000 women screenedFNs per 1000 women screenedTotal QALYs
Number of TPsQALYs of TPsNumber of FPsQALYs of FPsNumber of TNsQALYs of TNsNumber of FNsQALYs of FNs
Whooley questions followed by EPDS (≥ 13-point cut-off point)441333118642955917336.07
EPDS (≥ 13-point cut-off point) only461438138592935616336.10
Whooley questions followed by PHQ-962181558823014112336.27
Routine care case identification5115168577302495114336.15
Whooley questions followed by EPDS (≥ 10-point cut-off point)79238228815278237336.47
EPDS (≥ 10-point cut-off point) only852512141777265185336.53
Whooley questions only872614650751257154336.56

From: Chapter 7, Cost-effectiveness of screening/case-finding strategies for perinatal depression

Cover of Identifying perinatal depression with case-finding instruments: a mixed-methods study (BaBY PaNDA – Born and Bred in Yorkshire PeriNatal Depression Diagnostic Accuracy)
Identifying perinatal depression with case-finding instruments: a mixed-methods study (BaBY PaNDA – Born and Bred in Yorkshire PeriNatal Depression Diagnostic Accuracy).
Health Services and Delivery Research, No. 6.6.
Littlewood E, Ali S, Dyson L, et al.
Southampton (UK): NIHR Journals Library; 2018 Feb.
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