TABLE 24

Total costs, QALYs and probability of cost-effectiveness of screening/case-finding strategies for prenatal depression

StrategyTotal cost (£)Total QALYsICER (£)aProbability of cost-effectiveness for maximum WTP
£13,000£20,000£30,000
Whooley questions followed by EPDS (≥ 13-point cut-off point)49.200.33607–0.6500.4610.336
EPDS (≥ 13-point cut-off point) only52.800.33610Extendedly dominated0.0330.0390.047
Whooley questions followed by PHQ-955.100.3362728,9580.3160.4660.480
Routine care case identification68.400.33615Dominated0.0010.0010.001
Whooley questions followed by EPDS (≥ 10-point cut-off point)76.800.33647107,2220.0010.0190.065
EPDS (≥ 10-point cut-off point) only87.800.33653Extendedly dominated0.0000.0110.052
Whooley questions only91.600.33656171,9900.0000.0020.020
a

Dominated implies that the strategy has higher costs and lower QALYs than the comparator. Extended dominance implies that the ICER of this strategy is higher than the ICER of the next most effective strategy.

Strategies with the highest probability of being cost-effective at different WTP thresholds are shaded.

From: Chapter 7, Cost-effectiveness of screening/case-finding strategies for perinatal depression

Cover of Identifying perinatal depression with case-finding instruments: a mixed-methods study (BaBY PaNDA – Born and Bred in Yorkshire PeriNatal Depression Diagnostic Accuracy)
Identifying perinatal depression with case-finding instruments: a mixed-methods study (BaBY PaNDA – Born and Bred in Yorkshire PeriNatal Depression Diagnostic Accuracy).
Health Services and Delivery Research, No. 6.6.
Littlewood E, Ali S, Dyson L, et al.
Southampton (UK): NIHR Journals Library; 2018 Feb.
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