Table 3.56. Relative risks for coronary heart disease (CHD) associated with adult exposure to environmental tobacco smoke (ETS) among persons who never smoked or nonsmokers, case-control studies

StudyPopulation * SourceRelative risk ** (95% confidence interval)Adjustment factors
CasesControls
Lee et al. 1986 Women
7 cases
318 controls
Men
41 cases
133 controls
United Kingdom
HospitalHospitalWomen:
0.9 (0.6-1.7)
0.4 (0.1-1.4) **
Men:
1.2 (0.6-2.8)
0.8 (0.2-2.0)§
Not available
He 1989 Women >§<§
34 cases
68 controls
China
HospitalHospital and populationWomen: 1.5 (1.3-1.8)Alcohol use; exercise; personal and family history of CHD, hypertension, hyperlipidemia
Jackson 1989 Women¶
22 cases
174 controls
Men¶
44 cases
84 controls
New Zealand
Hospital
Myocardial infarction
Death from CHD
HospitalWomen: 2.7 (0.6-12.3)¶¶
Men: 1.0 (0.3-3.0)¶¶

Women: 5.8 (1.0-35.2)¶¶
Men: 1.1 (0.2-5.3)¶¶
Age, social status, history of CHD
Dobson et al. 1991b Women¶
160 cases
532 controls
Men¶
183 cases
293 controls
Australia
Hospital deaths from myocardial infarction and CHDCommunity-based surveyof riskWomen: 2.5 (1.5-4.1)¶¶
Men: 1.0 (0.5-1.8)¶¶
Age, history of myocardial infarction
La Vecchia et al. 1993a Women
43 cases
56 controls
Men
64 cases
161 controls
Italy
HospitalHospitalWomen and men: 1.2 (0.6-2.5) *** Gender, age, coffee intake, body mass index, cholesterol level, diabetes, hypertension, family history of myocardial infarction
He et al. 1994 Women
59 cases
126 controls
China
Hospital
Hospital
Population
Women:
1.2 (0.6-1.8)
1.9 (0.9-4.0)
Age, type A personality, total and high-density lipoprotein cholesterol levels, history of hypertension
Layard 1995 Women 914 cases 969 controls
Men 475 cases 998 controls
National Mortality Follow-back Survey
United States
Deaths from ischemic heart disease identified in surveyDeaths from unspecified causes not related to smokingWomen: 1.0 (0.8-1.2)
Men: 1.0 (0.7-1.3)
Age, race
Muscat and Wynder 1995a Women 46 cases
50 controls
Men 68 cases
108 controls
4 U.S. cities
HospitalHospitalWomen and men: 1.5 (0.9-2.6) ***
Women: 1.3 (0.7-2.4) ***
Men: 1.7 (0.7-3.7) ***
Age, education, hypertension
Tunstall-Pedoe et al. 1995 Women and men 70 cases
2,278 controls Scotland
General practitioner list; self-report of a diagnosed CHDGeneral practitioner list; self-report of a diagnosed CHDWomen and men:2.4 (1.1-4.8)§§ Age, housing, tenure, cholesterol level, diastolic blood pressure
Ciruzzi et al. 1998 Women 180 cases
218 controls
Men 156 cases
228 controls
10 South American countries
HospitalHospitalWomen: 1.5 (0.95-2.5)§§§§
Men: 1.9 (1.1-3.2)
Age, cholesterol level, diabetes, hypertension, body mass index, education, socioeconomic status, exercise, family history of myocardial infarction
*

Unless otherwise specified, study population never smoked.

**

Unless otherwise specified, relative risk from any exposure to ETS from spouse vs. no exposure.

§

ETS score 5-12 vs. 0-1, including ETS exposure at home, work, travel, and leisure.

>§<§

Nonsmokers.

but unclear whether population never smoked.

¶¶

For any exposure to ETS at home vs. no exposure.

***

Spouse was current smoker vs. spouse did not smoke.

***

For any ETS exposure including spouse, work, transportation, and other vs. no exposure.

§§

Any exposure to ETS from someone else in last 3 days.

§§§§

One or more relatives smoking.

From: Chapter 3. Health Consequences of Tobacco Use Among Women

Cover of Women and Smoking
Women and Smoking: A Report of the Surgeon General.
Office on Smoking and Health (US).

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