Table 3.31 Smoking and age at natural menopause

StudyPopulationDuration of amenorrhea before menopauseSmoking status comparisonDecrease in mean or median age at menopause (years)
Bailey et al. 1977 475 participants in health screening program
United Kingdom
NR * Current vs. former and never1.3 **
Jick et al. 1977 1,842 hospital patients
1,253 hospital patients
United States
NR
NR
Current vs. never
Current vs. never
1.7 **
1.3
McNamara et al. 1978 926 from general population
United States
12 monthsCurrent vs. never and former0.8§
Lindquist and Bengtsson 1979 873 from population sample
Sweden
5 monthsCurrent vs. never and former1.2 **
Kaufman et al. 1980 656 hospital patients
United States
NRCurrent vs. never
Former vs. never
1.7 >§<§
0.2 >§<§
Adena and Gallagher 1982 10,995 participants in multiphasic health screening program
Australia
6 monthsCurrent vs. never
Former vs. never
1.0 ** 0.4§
Andersen et al. 1982b5,645 from population sample
Denmark
6 monthsCurrent vs. never and former1.0§
Willett et al. 1983 66,663 nurses
United States
NRCurrent (15-25 cigarettes/day) vs. never1.4§
McKinlay et al. 1985 5,350 from population sample
United States
12 monthsCurrent vs. never and former1.7§
Everson et al. 1986 261 controls
United States
NRCurrent vs. never1.1§
Hiatt and Fireman 1986 5,346 health maintenance organization members with multiphasic health examination United StatesNRCurrent vs. never Former vs. never0.9 **
0.5 **
Stanford et al. 1987a 1,472 participants in mammography screening program
United States
3 monthsEver vs. never0.3§
McKinlay et al. 1992 2,570 from population sample
United States
12 monthsCurrent vs. never and former1.8§
Luoto et al. 1994 1,505 from population sample
Finland
NRCurrent vs. never and former1.6§
Willett et al. 1983 66,663 nurses
United States
NRCurrent (15-25 cigarettes/day) vs. never1.4§
McKinlay et al. 1985 5,350 from population sample
United States
12 monthsCurrent vs. never and former1.7§
Everson et al. 1986 261 controls
United States
NRCurrent vs. never1.1§
Hiatt and Fireman 1986 5,346 health maintenance organization members with multiphasic health examination United StatesNRCurrent vs. never Former vs. never0.9 **
0.5 **
Stanford et al. 1987a 1,472 participants in mammography screening program
United States
3 monthsEver vs. never0.3§
McKinlay et al. 1992 2,570 from population sample
United States
12 monthsCurrent vs. never and former1.8§
Luoto et al. 1994 1,505 from population sample
Finland
NRCurrent vs. never and former1.6§
*

NR = Value not specified in report of study.

**Difference in mean ages.

§

§Difference in median ages.

>§<§Difference in ages at menopause computed by Adena and Gallagher (1982).

From: Chapter 3. Health Consequences of Tobacco Use Among Women

Cover of Women and Smoking
Women and Smoking: A Report of the Surgeon General.
Office on Smoking and Health (US).

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