Table 3.30. Findings regarding smoking and menstrual irregularity or secondary amenorrhea

StudyStudy type/
population
Findings
Menstrual irregularitySecondary amenorrhea
Hammond 1961 Cohort
Aged 30-39study
United States
Prevalence
Aged years
1,050 never smoked: 16.3% *
842 current smokers: 18.2% *
Pettersson et al. 1973 Population survey Aged 18-45 years
Sweden
Prevalence
824 never smoked: 3.7%
262 former smokers: 5.9%
773 current smokers: 4.8%
Brown et al. 1988 Medical practice-based
survey
Aged 18-49 years
England
Prevalence
1,006 never smoked: 8.9%
458 former smokers: 9.0%
628 current smokers: 14.6%
Davies et al. 1990 Case-control study
Clinic patients
Aged 16-40 years
England
Unadjusted relative risk for
ever smoking and
amenorrhea = 2.1 **
Johnson and Whitaker 1992 Population survey High school students
United States
Adjusted relative risk for
smokers of > 1 pack/day:
2.0 (95% confidence
interval, 1.2-3.1)
Hornsby et al. 1998 Follow-up study
Aged 37-39 years United States
Standard deviation of cycle
length
275 nonsmokers: 2.1 days
83 smokers: 2.5 days
*

Amenorrhea among women who ever had menstrual periods.

**

Computed from data presented in report.

From: Chapter 3. Health Consequences of Tobacco Use Among Women

Cover of Women and Smoking
Women and Smoking: A Report of the Surgeon General.
Office on Smoking and Health (US).

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