Table 3.25. Relative risks for stroke among women for current smokers compared with nonsmokers, cohort studies

StudyPopulationNumber of years of follow-upOutcomeSmoking statusRelative risk (95% confidence interval)
Hirayama 1990 142,857 women
Aged > 40 years
Sampled from census
Japan
17Death from cerebrovascular diseaseNonsmokers1.0
Current smokers
1-9 cigarettes/day
1.2 (1.1-1.3) *
10-19 cigarettes/day1.1 (0.99-1.2) *
> 20 cigarettes/day1.3 (1.1-1.6) *
Death from subarachnoid hemorrhageNonsmokers1.0
Current smokers
1-9 cigarettes/day
1.5 (1.2-2.5)
10-19 cigarettes/day1.4 (0.9-2.2)
> 20 cigarettes/day2.1 (0.9-4.6)
Kiyohara et al. 1990 904 women
Aged >40 years
Japan
23Nonembolic cerebral infarctionNever smoked
Current smokers
1.0
0.8 (0.4-1.4)
Knekt et al. 1991 Population samples
Aged 20-69 years
Finland
12Subarachnoid hemorrhageNonsmokers
Current smokers
1.0
2.4 (1.4-4.0)
Kawachi et al. 1993b 117,006 women nurses
Aged 30-55 years
United States
12Total strokeNever smoked1.0
Current smokers
1-14 cigarettes/day
2.0 (1.3-3.1)
15-24 cigarettes/day3.3 (2.4-4.7)
25-34 cigarettes/day3.1 (1.9-4.9)
> 35 cigarettes/day4.5 (2.8-7.2)
Subarachnoid hemorrhageNever smoked
Current smokers
1.0
4.9 (2.9-8.1)
Kawachi et al. 1993b (continued)Ischemic strokeNever smoked
Current smokers
1.0
2.5 (1.9-3.4)
Cerebral hemorrhageNever smoked
Current smokers
1.0
1.4 (0.8-2.8)
Lindenstrøm et al. 1993 7,060 women
Aged >35 years
Denmark
12Total stroke or transient ischemic attackNever smoked
Current smokers
1.0
1.4 (1.02-1.9)
Burns et al. 1997b 594,551 women
Aged >30 years
25 U.S. states
12Death from strokeNever smoked1.0
Current smokers
Aged 35-49 years
2.5 **
Aged 50-64 years2.2 **
Aged 65-79 years1.3 **
Aged > 80 years0.8 **
Friedman et al. 1997 (see Table 3.23)36,035 women
Aged > 35 years
United States
6Death from strokeNever smoked1.0
Current smokers
1-19 cigarettes/day
0.9 **
> 20 cigarettes/day1.9 **
Thun et al. 1997c 676,527 women
Aged >30 years
50 U.S. states
6Death from strokeNever smoked
Current smokers
1.0
1.5 (1.2-1.7)
*

90% confidence interval.

**

95% confidence interval was not reported.

From: Chapter 3. Health Consequences of Tobacco Use Among Women

Cover of Women and Smoking
Women and Smoking: A Report of the Surgeon General.
Office on Smoking and Health (US).

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