| Outcomes | No of Participants (studies) Follow up | Quality of the evidence (GRADE) | Anticipated absolute effects | |
|---|---|---|---|---|
| Risk with Control | Risk difference with Mixed modality manual therapy versus soft tissue technique (95% CI) | |||
| Pain severity (VAS, 0-10) ≤4 months | 97 (1 study) | VERY LOWa,b due to risk of bias, imprecision | The mean pain severity (VAS 0-10) <4 months in the control groups was 2.78 | The mean pain severity (VAS 0-10) ≤4 months in the intervention groups was 0.74 lower (1.38 to 0.1 lower) |
| Pain severity (VAS, 0-10) > 4 months | 96 (1 study) | VERY LOWa,b due to risk of bias, imprecision | The mean pain severity (VAS 0-10) > 4 months in the control groups was 2.99 | The mean pain severity (VAS 0-10) > 4 months in the intervention groups was 0.75 lower (1.61 lower to 0.11 higher) |
| Function (RMDQ, 0-24) ≤4 months | 97 (1 study) | VERY LOWa,b due to risk of bias, imprecision | The mean function (RMDQ 0-24) <4 months in the control groups was 5.8 | The mean function (RMDQ 0-24) ≤4 months in the intervention groups was 2.07 lower (3.86 to 0.28 lower) |
| Function (RMDQ, 0-24)> 4 months | 95 (1 study) | VERY LOWa,b due to risk of bias, imprecision | The mean function (RMDQ 0-24) > 4 months in the control groups was 5.06 | The mean function (RMDQ 0-24) > 4 months in the intervention groups was 1.5 lower (3.18 lower to 0.18 higher) |
Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias
Downgraded by 1 increment if the confidence interval crossed 1 MID or by 2 increments if the confidence interval crossed both MIDs
From: 12, Manual therapies
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