TABLE 38

Composition of the case–control data set

Parameter assessmentControl subjects (N = 972), n (%)Case subjects (N = 324), n (%)
Age (years)
 < 5053 (5.5)19 (5.9)
 50–54252 (25.9)82 (25.3)
 55–59154 (15.8)52 (16.0)
 60–64234 (24.1)78 (24.1)
 65–69199 (20.5)67 (20.7)
 ≥ 7080 (8.2)26 (8.0)
 Mean (SD)59.99 (7.05)60.02 (7.17)
Menopausal status
 Perimenopausal116 (11.9)38 (11.7)
 Postmenopausal717 (73.8)241 (74.4)
 Premenopausal96 (9.9)33 (10.2)
 Unknown43 (4.4)12 (3.7)
HRT
 Never583 (60.0)212 (65.4)
 Previous335 (34.5)92 (28.4)
 Current54 (5.6)18 (5.6)
BMI (kg/m2)
 < 25281 (28.9)92 (28.4)
 25–29342 (35.2)112 (34.6)
 ≥ 30287 (29.5)95 (29.3)
 Unknown62 (6.4)25 (7.7)
 Mean (SD)28.41 (5.71)28.08 (5.19)
Ethnic origin
 Asian/Asian British6 (0.6)3 (0.9)
 Black/black British11 (1.1)0 (0)
 Jewish10 (1)1 (0.3)
 Mixed6 (0.6)3 (0.9)
 Other15 (1.5)9 (2.8)
 White917 (94.3)300 (92.6)
Initial TC
 Mean (SD)3.13 (1.42)3.53 (2.29)
Alcohol
 No254 (26.1)76 (23.5)
 Yes702 (72.2)240 (74.1)
 Unknown16 (1.6)8 (2.5)
Any children
 No112 (11.5)40 (12.3)
 Yes859 (88.4)284 (87.7)
Biopsy of breast
 No794 (81.7)254 (78.4)
 Yes151 (15.5)57 (17.6)
 Not known27 (2.8)13 (4.0)

SD, standard deviation.

From: Chapter 4, PROCAS: Predicting Risk of Breast Cancer at Screening

Cover of Improvement in risk prediction, early detection and prevention of breast cancer in the NHS Breast Screening Programme and family history clinics: a dual cohort study
Improvement in risk prediction, early detection and prevention of breast cancer in the NHS Breast Screening Programme and family history clinics: a dual cohort study.
Programme Grants for Applied Research, No. 4.11.
Evans DG, Astley S, Stavrinos P, et al.
Southampton (UK): NIHR Journals Library; 2016 Aug.
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