Table 14Change in World Health Organization Functional Class

VisitWHO
Functional
Class
Riociguat (n = 173)Placebo (n = 88)
Baselinen▬▬▬▬▬▬▬▬
I▬▬▬▬▬▬▬▬
II▬▬▬▬▬▬▬▬
III▬▬▬▬▬▬▬▬
IV▬▬▬▬▬▬▬▬
Last Visitn▬▬▬▬▬▬▬▬
I▬▬▬▬▬▬▬▬
II▬▬▬▬▬▬▬▬
III▬▬▬▬▬▬▬▬
IV▬▬▬▬▬▬▬▬
Va▬▬▬▬▬▬▬▬
Change From Baseline at Last Visitn▬▬▬▬▬▬▬▬
−2▬▬▬▬▬▬▬▬
−1▬▬▬▬▬▬▬▬
0▬▬▬▬▬▬▬▬
1▬▬▬▬▬▬▬▬
2▬▬▬▬▬▬▬▬
3▬▬▬▬▬▬▬▬
P value (stratified Wilcoxon test)▬▬▬▬

WHO = World Health Organization.

a

V represented an imputed worst value in case of death.

From: APPENDIX 4, DETAILED OUTCOME DATA

Cover of Riociguat (Adempas)
Riociguat (Adempas): Management of Inoperable Chronic Thromboembolic Pulmonary Hypertension [Internet].
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