Cost-effectiveness supplementary tables

Augusto Azuara-Blanco; Katie Banister; Charles Boachie; Peter McMeekin; Joanne Gray; Jennifer Burr; Rupert Bourne; David Garway-Heath; Mark Batterbury; Rodolfo Hernández; Gladys McPherson; Craig Ramsay; Jonathan Cook

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Azuara-Blanco A, Banister K, Boachie C, et al. Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study). Southampton (UK): NIHR Journals Library; 2016 Jan. (Health Technology Assessment, No. 20.8.)

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Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study).

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Appendix 7Cost-effectiveness supplementary tables

TABLE 63

Incremental cost-effectiveness for the base case with different NHS Reference Costs applied to the triage strategies

NHS Reference Cost (£)	Intervention	Cost (£)	QALYs	ICER
10	GDx	2841	19.7701	–
	OCT	2967	19.7746	27,812
	HRT-MRA	3001	19.7771	13,807
	HRT-GPS	3011	19.7771	Dominated^a
	Current practice	3084	19.7780	98,231
13	GDx	2856	19.7701	–
	OCT	2982	19.7746	27,784
	HRT-MRA	3016	19.7771	13,780
	HRT-GPS	3026	19.7771	Dominated^a
	Current practice	3084	19.7780	80,605
16	GDx	2872	19.7701	–
	OCT	2996	19.7746	27,757
	HRT-MRA	3031	19.7771	13,754
	HRT-GPS	3040	19.7771	Dominated^a
	Current practice	3084	19.7780	62,979
19	GDx	2887	19.7701	–
	OCT	3011	19.7746	27,729
	HRT-MRA	3046	19.7771	13,727
	HRT-GPS	3055	19.7771	Dominated^a
	Current practice	3084	19.7780	45,353
22	GDx	2902	19.7701	–
	OCT	3026	19.7746	27,701
	HRT-MRA	3060	19.7771	13,700
	HRT-GPS	3070	19.7771	Dominated^a
	Current practice	3084	19.7780	27,727
25	GDx	2917	19.7701	–
	OCT	3041	19.7746	27,673
	HRT-MRA	3075	19.7771	13,673
	Current practice	3084	19.7780	10,101
	HRT-GPS	3085	19.7771	Dominated^a
28	GDx	2932	19.7701	–
	OCT	3056	19.7746	27,646
	Current practice	3084	19.7780	8313
	HRT-MRA	3090	19.7771	Dominated^a
	HRT-GPS	3100	19.7771	Dominated^a
31	GDx	2947	19.7701	–
	OCT	3071	19.7746	27,618
	Current practice	3084	19.7780	3853
	HRT-MRA	3105	19.7771	Dominated^a
	HRT-GPS	3115	19.7771	Dominated^a
34	GDx	2962	19.7701	–
	Current practice	3084	19.7780	15,579
	OCT	3086	19.7746	Dominated^a
	HRT-MRA	3120	19.7771	Dominated^a
	HRT-GPS	3129	19.7771	Dominated^a
37	GDx	2977	19.7701	–
	Current practice	3084	19.7780	13,663
	OCT	3101	19.7746	Dominated^a
	HRT-MRA	3135	19.7771	Dominated^a
	HRT-GPS	3144	19.7771	Dominated^a
40	GDx	2992	19.7701	–
	Current practice	3084	19.7780	11,747
	OCT	3116	19.7746	Dominated^a
	HRT-MRA	3149	19.7771	Dominated^a
	HRT-GPS	3159	19.7771	Dominated^a
43	GDx	3007	19.7701	–
	Current practice	3084	19.7780	9831
	OCT	3130	19.7746	Dominated^a
	HRT-MRA	3164	19.7771	Dominated^a
	HRT-GPS	3174	19.7771	Dominated^a
46	GDx	3022	19.7701	–
	Current practice	3084	19.7780	7315
	OCT	3145	19.7746	Dominated^a
	HRT-MRA	3179	19.7771	Dominated^a
	HRT-GPS	3189	19.7771	Dominated^a
49	GDx	3037	19.7701	–
	Current practice	3084	19.7780	5999
	OCT	3160	19.7746	Dominated^a
	HRT-MRA	3194	19.7771	Dominated^a
	HRT-GPS	3204	19.7771	Dominated^a
52	GDx	3052	19.7701	–
	Current practice	3084	19.7780	4083
	OCT	3175	19.7746	Dominated^a
	HRT-MRA	3209	19.7771	Dominated^a
	HRT-GPS	3218	19.7771	Dominated^a
55	GDx	3067	19.7701	–
	Current practice	3084	19.7780	2168
	OCT	3190	19.7746	Dominated^a
	HRT-MRA	3224	19.7771	Dominated^a
	HRT-GPS	3233	19.7771	Dominated^a
58	GDx	3082	19.7701	–
	Current practice	3084	19.7780	252
	OCT	3205	19.7746	Dominated^a
	HRT-MRA	3238	19.7771	Dominated^a
	HRT-GPS	3248	19.7771	Dominated^a
61	Current practice	3084	19.7780	–
	GDx	3097	19.7701	Dominated^a
	OCT	3220	19.7746	Dominated^a
	HRT-MRA	3253	19.7771	Dominated^a
	HRT-GPS	3263	19.7771	Dominated^a
64	Current practice	3084	19.7780	–
	GDx	3112	19.7701	Dominated^a
	OCT	3235	19.7746	Dominated^a
	HRT-MRA	3268	19.7771	Dominated^a
	HRT-GPS	3278	19.7771	Dominated^a
67	Current practice	3084	19.7780	–
	GDx	3127	19.7701	Dominated^a
	OCT	3250	19.7746	Dominated^a
	HRT-MRA	3283	19.7771	Dominated^a
	HRT-GPS	3292	19.7771	Dominated^a
70	Current practice	3084	19.7780	–
	GDx	3142	19.7701	Dominated^a
	OCT	3265	19.7746	Dominated^a
	HRT-MRA	3298	19.7771	Dominated^a
	HRT-GPS	3307	19.7771	Dominated^a
73	Current practice	3084	19.7780	–
	GDx	3157	19.7701	Dominated^a
	OCT	3279	19.7746	Dominated^a
	HRT-MRA	3313	19.7771	Dominated^a
	HRT-GPS	3322	19.7771	Dominated^a
76	Current practice	3084	19.7780	–
	GDx	3172	19.7701	Dominated^a
	OCT	3294	19.7746	Dominated^a
	HRT-MRA	3327	19.7771	Dominated^a
	HRT-GPS	3337	19.7771	Dominated^a
79	Current practice	3084	19.7780	–
	GDx	3187	19.7701	Dominated^a
	OCT	3309	19.7746	Dominated^a
	HRT-MRA	3342	19.7771	Dominated^a
	HRT-GPS	3352	19.7771	Dominated^a
82	Current practice	3084	19.7780	–
	GDx	3202	19.7701	Dominated^a
	OCT	3324	19.7746	Dominated^a
	HRT-MRA	3357	19.7771	Dominated^a
	HRT-GPS	3367	19.7771	Dominated^a
85	Current practice	3084	19.7780	–
	GDx	3217	19.7701	Dominated^a
	OCT	3339	19.7746	Dominated^a
	HRT-MRA	3372	19.7771	Dominated^a
	HRT-GPS	3381	19.7771	Dominated^a

a: Dominated: an intervention is more costly but is less effective or as effective as an intervention that is less costly.

TABLE 64

Incremental cost-effectiveness ratios of increasing costs of triage strategies and not treating patients diagnosed as ‘at risk’

Increasing cost of triage strategy (£)	Intervention	Cost (£)	QALYs	ICER
+ 10	GDx	2719	19.7393	–
	OCT	2840	19.7410	68,260
	HRT-MRA	2869	19.7414	83,488
	HRT-GPS	2879	19.7414	Dominated^a
	Current practice	2954	19.7415	488,759
+ 13	GDx	2733	19.7393	–
	OCT	2853	19.7410	68,229
	HRT-MRA	2883	19.7414	83,457
	HRT-GPS	2893	19.7414	Dominated^a
	Current practice	2954	19.7415	409,713
+ 16	GDx	2747	19.7393	–
	OCT	2867	19.7410	68,198
	HRT-MRA	2897	19.7414	83,426
	HRT-GPS	2906	19.7414	Dominated^a
	Current practice	2954	19.7415	330,667
+ 19	GDx	2761	19.7393	–
	OCT	2881	19.7410	68,167
	HRT-MRA	2910	19.7414	83,396
	HRT-GPS	2920	19.7414	Dominated^a
	Current practice	2954	19.7415	251,620
+ 22	GDx	2775	19.7393	–
	OCT	2895	19.7410	68,137
	HRT-MRA	2924	19.7414	83,365
	HRT-GPS	2934	19.7414	Dominated^a
	Current practice	2954	19.7415	172,574
+ 25	GDx	2788	19.7393	–
	OCT	2908	19.7410	68,106
	HRT-MRA	2938	19.7414	83,335
	HRT-GPS	2947	19.7414	Dominated^a
	Current practice	2954	19.7415	93,527
+ 28	GDx	2802	19.7393	–
	OCT	2922	19.7410	68,075
	HRT-MRA	2952	19.7414	83,304
	Current practice	2954	19.7415	14,481
	HRT-GPS	2961	19.7414	Dominated^a
+ 31	GDx	2816	19.7393	–
	OCT	2936	19.7410	68,044
	Current practice	2954	19.7415	34,813
	HRT-MRA	2965	19.7414	Dominated^a
	HRT-GPS	2975	19.7414	Dominated^a
+ 34	GDx	2830	19.7393	–
	OCT	2949	19.7410	68,014
	Current practice	2954	19.7415	8882
	HRT-MRA	2979	19.7414	Dominated^a
	HRT-GPS	2989	19.7414	Dominated^a
+ 37	GDx	2843	19.7393	–
	Current practice	2954	19.7415	48,341
	OCT	2963	19.7410	Dominated^a
	HRT-MRA	2993	19.7414	Dominated^a
	HRT-GPS	3002	19.7414	Dominated^a
+ 40	GDx	2857	19.7393	0
	Current practice	2954	19.7415	42,328
	OCT	2977	19.7410	Dominated^a
	HRT-MRA	3006	19.7414	Dominated^a
	HRT-GPS	3016	19.7414	Dominated^a
+ 43	GDx	2871	19.7393	–
	Current practice	2954	19.7415	36,314
	OCT	2991	19.7410	Dominated^a
	HRT-MRA	3020	19.7414	Dominated^a
	HRT-GPS	3030	19.7414	Dominated^a
+ 46	GDx	2885	19.7393	–
	Current practice	2954	19.7415	30,300
	OCT	3004	19.7410	Dominated^a
	HRT-MRA	3034	19.7414	Dominated^a
	HRT-GPS	3043	19.7414	Dominated^a
+ 49	GDx	2898	19.7393	–
	Current practice	2954	19.7415	24,287
	OCT	3018	19.7410	Dominated^a
	HRT-MRA	3048	19.7414	Dominated^a
	HRT-GPS	3057	19.7414	Dominated^a
+ 52	GDx	2912	19.7393	–
	Current practice	2954	19.7415	18,273
	OCT	3032	19.7410	Dominated^a
	HRT-MRA	3061	19.7414	Dominated^a
	HRT-GPS	3071	19.7414	Dominated^a
+ 55	GDx	2926	19.7393	–
	Current practice	2954	19.7415	12,260
	OCT	3045	19.7410	Dominated^a
	HRT-MRA	3075	19.7414	Dominated^a
	HRT-GPS	3084	19.7414	Dominated^a
+ 58	GDx	2940	19.7393	–
	Current practice	2954	19.7415	6246
	OCT	3059	19.7410	Dominated^a
	HRT-MRA	3089	19.7414	Dominated^a
	HRT-GPS	3098	19.7414	Dominated^a
+ 61	GDx	2954	19.7393	–
	Current practice	2954	19.7415	233
	OCT	3073	19.7410	Dominated^a
	HRT-MRA	3102	19.7414	Dominated^a
	HRT-GPS	3112	19.7414	Dominated^a
+ 64	Current practice	2954	19.7415	–
	GDx	2967	19.7393	Dominated^a
	OCT	3087	19.7410	Dominated^a
	HRT-MRA	3116	19.7414	Dominated^a
	HRT-GPS	3126	19.7414	Dominated^a
+ 67	Current practice	2954	19.7415	–
	GDx	2981	19.7393	Dominated^a
	OCT	3100	19.7410	Dominated^a
	HRT-MRA	3130	19.7414	Dominated^a
	HRT-GPS	3139	19.7414	Dominated^a

a: Dominated: an intervention is more costly but is less effective or as effective as an intervention that is less costly.

Copyright © Queen’s Printer and Controller of HMSO 2016. This work was produced by Azuara-Blanco et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK338825

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Azuara-Blanco A, Banister K, Boachie C, et al. Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study). Southampton (UK): NIHR Journals Library; 2016 Jan. (Health Technology Assessment, No. 20.8.) Appendix 7, Cost-effectiveness supplementary tables.
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