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Azuara-Blanco A, Banister K, Boachie C, et al. Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study). Southampton (UK): NIHR Journals Library; 2016 Jan. (Health Technology Assessment, No. 20.8.)
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Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study).
Show detailsTABLE 63
Incremental cost-effectiveness for the base case with different NHS Reference Costs applied to the triage strategies
NHS Reference Cost (£) | Intervention | Cost (£) | QALYs | ICER |
---|---|---|---|---|
10 | GDx | 2841 | 19.7701 | – |
OCT | 2967 | 19.7746 | 27,812 | |
HRT-MRA | 3001 | 19.7771 | 13,807 | |
HRT-GPS | 3011 | 19.7771 | Dominateda | |
Current practice | 3084 | 19.7780 | 98,231 | |
13 | GDx | 2856 | 19.7701 | – |
OCT | 2982 | 19.7746 | 27,784 | |
HRT-MRA | 3016 | 19.7771 | 13,780 | |
HRT-GPS | 3026 | 19.7771 | Dominateda | |
Current practice | 3084 | 19.7780 | 80,605 | |
16 | GDx | 2872 | 19.7701 | – |
OCT | 2996 | 19.7746 | 27,757 | |
HRT-MRA | 3031 | 19.7771 | 13,754 | |
HRT-GPS | 3040 | 19.7771 | Dominateda | |
Current practice | 3084 | 19.7780 | 62,979 | |
19 | GDx | 2887 | 19.7701 | – |
OCT | 3011 | 19.7746 | 27,729 | |
HRT-MRA | 3046 | 19.7771 | 13,727 | |
HRT-GPS | 3055 | 19.7771 | Dominateda | |
Current practice | 3084 | 19.7780 | 45,353 | |
22 | GDx | 2902 | 19.7701 | – |
OCT | 3026 | 19.7746 | 27,701 | |
HRT-MRA | 3060 | 19.7771 | 13,700 | |
HRT-GPS | 3070 | 19.7771 | Dominateda | |
Current practice | 3084 | 19.7780 | 27,727 | |
25 | GDx | 2917 | 19.7701 | – |
OCT | 3041 | 19.7746 | 27,673 | |
HRT-MRA | 3075 | 19.7771 | 13,673 | |
Current practice | 3084 | 19.7780 | 10,101 | |
HRT-GPS | 3085 | 19.7771 | Dominateda | |
28 | GDx | 2932 | 19.7701 | – |
OCT | 3056 | 19.7746 | 27,646 | |
Current practice | 3084 | 19.7780 | 8313 | |
HRT-MRA | 3090 | 19.7771 | Dominateda | |
HRT-GPS | 3100 | 19.7771 | Dominateda | |
31 | GDx | 2947 | 19.7701 | – |
OCT | 3071 | 19.7746 | 27,618 | |
Current practice | 3084 | 19.7780 | 3853 | |
HRT-MRA | 3105 | 19.7771 | Dominateda | |
HRT-GPS | 3115 | 19.7771 | Dominateda | |
34 | GDx | 2962 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 15,579 | |
OCT | 3086 | 19.7746 | Dominateda | |
HRT-MRA | 3120 | 19.7771 | Dominateda | |
HRT-GPS | 3129 | 19.7771 | Dominateda | |
37 | GDx | 2977 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 13,663 | |
OCT | 3101 | 19.7746 | Dominateda | |
HRT-MRA | 3135 | 19.7771 | Dominateda | |
HRT-GPS | 3144 | 19.7771 | Dominateda | |
40 | GDx | 2992 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 11,747 | |
OCT | 3116 | 19.7746 | Dominateda | |
HRT-MRA | 3149 | 19.7771 | Dominateda | |
HRT-GPS | 3159 | 19.7771 | Dominateda | |
43 | GDx | 3007 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 9831 | |
OCT | 3130 | 19.7746 | Dominateda | |
HRT-MRA | 3164 | 19.7771 | Dominateda | |
HRT-GPS | 3174 | 19.7771 | Dominateda | |
46 | GDx | 3022 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 7315 | |
OCT | 3145 | 19.7746 | Dominateda | |
HRT-MRA | 3179 | 19.7771 | Dominateda | |
HRT-GPS | 3189 | 19.7771 | Dominateda | |
49 | GDx | 3037 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 5999 | |
OCT | 3160 | 19.7746 | Dominateda | |
HRT-MRA | 3194 | 19.7771 | Dominateda | |
HRT-GPS | 3204 | 19.7771 | Dominateda | |
52 | GDx | 3052 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 4083 | |
OCT | 3175 | 19.7746 | Dominateda | |
HRT-MRA | 3209 | 19.7771 | Dominateda | |
HRT-GPS | 3218 | 19.7771 | Dominateda | |
55 | GDx | 3067 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 2168 | |
OCT | 3190 | 19.7746 | Dominateda | |
HRT-MRA | 3224 | 19.7771 | Dominateda | |
HRT-GPS | 3233 | 19.7771 | Dominateda | |
58 | GDx | 3082 | 19.7701 | – |
Current practice | 3084 | 19.7780 | 252 | |
OCT | 3205 | 19.7746 | Dominateda | |
HRT-MRA | 3238 | 19.7771 | Dominateda | |
HRT-GPS | 3248 | 19.7771 | Dominateda | |
61 | Current practice | 3084 | 19.7780 | – |
GDx | 3097 | 19.7701 | Dominateda | |
OCT | 3220 | 19.7746 | Dominateda | |
HRT-MRA | 3253 | 19.7771 | Dominateda | |
HRT-GPS | 3263 | 19.7771 | Dominateda | |
64 | Current practice | 3084 | 19.7780 | – |
GDx | 3112 | 19.7701 | Dominateda | |
OCT | 3235 | 19.7746 | Dominateda | |
HRT-MRA | 3268 | 19.7771 | Dominateda | |
HRT-GPS | 3278 | 19.7771 | Dominateda | |
67 | Current practice | 3084 | 19.7780 | – |
GDx | 3127 | 19.7701 | Dominateda | |
OCT | 3250 | 19.7746 | Dominateda | |
HRT-MRA | 3283 | 19.7771 | Dominateda | |
HRT-GPS | 3292 | 19.7771 | Dominateda | |
70 | Current practice | 3084 | 19.7780 | – |
GDx | 3142 | 19.7701 | Dominateda | |
OCT | 3265 | 19.7746 | Dominateda | |
HRT-MRA | 3298 | 19.7771 | Dominateda | |
HRT-GPS | 3307 | 19.7771 | Dominateda | |
73 | Current practice | 3084 | 19.7780 | – |
GDx | 3157 | 19.7701 | Dominateda | |
OCT | 3279 | 19.7746 | Dominateda | |
HRT-MRA | 3313 | 19.7771 | Dominateda | |
HRT-GPS | 3322 | 19.7771 | Dominateda | |
76 | Current practice | 3084 | 19.7780 | – |
GDx | 3172 | 19.7701 | Dominateda | |
OCT | 3294 | 19.7746 | Dominateda | |
HRT-MRA | 3327 | 19.7771 | Dominateda | |
HRT-GPS | 3337 | 19.7771 | Dominateda | |
79 | Current practice | 3084 | 19.7780 | – |
GDx | 3187 | 19.7701 | Dominateda | |
OCT | 3309 | 19.7746 | Dominateda | |
HRT-MRA | 3342 | 19.7771 | Dominateda | |
HRT-GPS | 3352 | 19.7771 | Dominateda | |
82 | Current practice | 3084 | 19.7780 | – |
GDx | 3202 | 19.7701 | Dominateda | |
OCT | 3324 | 19.7746 | Dominateda | |
HRT-MRA | 3357 | 19.7771 | Dominateda | |
HRT-GPS | 3367 | 19.7771 | Dominateda | |
85 | Current practice | 3084 | 19.7780 | – |
GDx | 3217 | 19.7701 | Dominateda | |
OCT | 3339 | 19.7746 | Dominateda | |
HRT-MRA | 3372 | 19.7771 | Dominateda | |
HRT-GPS | 3381 | 19.7771 | Dominateda |
- a
Dominated: an intervention is more costly but is less effective or as effective as an intervention that is less costly.
TABLE 64
Incremental cost-effectiveness ratios of increasing costs of triage strategies and not treating patients diagnosed as ‘at risk’
Increasing cost of triage strategy (£) | Intervention | Cost (£) | QALYs | ICER |
---|---|---|---|---|
+ 10 | GDx | 2719 | 19.7393 | – |
OCT | 2840 | 19.7410 | 68,260 | |
HRT-MRA | 2869 | 19.7414 | 83,488 | |
HRT-GPS | 2879 | 19.7414 | Dominateda | |
Current practice | 2954 | 19.7415 | 488,759 | |
+ 13 | GDx | 2733 | 19.7393 | – |
OCT | 2853 | 19.7410 | 68,229 | |
HRT-MRA | 2883 | 19.7414 | 83,457 | |
HRT-GPS | 2893 | 19.7414 | Dominateda | |
Current practice | 2954 | 19.7415 | 409,713 | |
+ 16 | GDx | 2747 | 19.7393 | – |
OCT | 2867 | 19.7410 | 68,198 | |
HRT-MRA | 2897 | 19.7414 | 83,426 | |
HRT-GPS | 2906 | 19.7414 | Dominateda | |
Current practice | 2954 | 19.7415 | 330,667 | |
+ 19 | GDx | 2761 | 19.7393 | – |
OCT | 2881 | 19.7410 | 68,167 | |
HRT-MRA | 2910 | 19.7414 | 83,396 | |
HRT-GPS | 2920 | 19.7414 | Dominateda | |
Current practice | 2954 | 19.7415 | 251,620 | |
+ 22 | GDx | 2775 | 19.7393 | – |
OCT | 2895 | 19.7410 | 68,137 | |
HRT-MRA | 2924 | 19.7414 | 83,365 | |
HRT-GPS | 2934 | 19.7414 | Dominateda | |
Current practice | 2954 | 19.7415 | 172,574 | |
+ 25 | GDx | 2788 | 19.7393 | – |
OCT | 2908 | 19.7410 | 68,106 | |
HRT-MRA | 2938 | 19.7414 | 83,335 | |
HRT-GPS | 2947 | 19.7414 | Dominateda | |
Current practice | 2954 | 19.7415 | 93,527 | |
+ 28 | GDx | 2802 | 19.7393 | – |
OCT | 2922 | 19.7410 | 68,075 | |
HRT-MRA | 2952 | 19.7414 | 83,304 | |
Current practice | 2954 | 19.7415 | 14,481 | |
HRT-GPS | 2961 | 19.7414 | Dominateda | |
+ 31 | GDx | 2816 | 19.7393 | – |
OCT | 2936 | 19.7410 | 68,044 | |
Current practice | 2954 | 19.7415 | 34,813 | |
HRT-MRA | 2965 | 19.7414 | Dominateda | |
HRT-GPS | 2975 | 19.7414 | Dominateda | |
+ 34 | GDx | 2830 | 19.7393 | – |
OCT | 2949 | 19.7410 | 68,014 | |
Current practice | 2954 | 19.7415 | 8882 | |
HRT-MRA | 2979 | 19.7414 | Dominateda | |
HRT-GPS | 2989 | 19.7414 | Dominateda | |
+ 37 | GDx | 2843 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 48,341 | |
OCT | 2963 | 19.7410 | Dominateda | |
HRT-MRA | 2993 | 19.7414 | Dominateda | |
HRT-GPS | 3002 | 19.7414 | Dominateda | |
+ 40 | GDx | 2857 | 19.7393 | 0 |
Current practice | 2954 | 19.7415 | 42,328 | |
OCT | 2977 | 19.7410 | Dominateda | |
HRT-MRA | 3006 | 19.7414 | Dominateda | |
HRT-GPS | 3016 | 19.7414 | Dominateda | |
+ 43 | GDx | 2871 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 36,314 | |
OCT | 2991 | 19.7410 | Dominateda | |
HRT-MRA | 3020 | 19.7414 | Dominateda | |
HRT-GPS | 3030 | 19.7414 | Dominateda | |
+ 46 | GDx | 2885 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 30,300 | |
OCT | 3004 | 19.7410 | Dominateda | |
HRT-MRA | 3034 | 19.7414 | Dominateda | |
HRT-GPS | 3043 | 19.7414 | Dominateda | |
+ 49 | GDx | 2898 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 24,287 | |
OCT | 3018 | 19.7410 | Dominateda | |
HRT-MRA | 3048 | 19.7414 | Dominateda | |
HRT-GPS | 3057 | 19.7414 | Dominateda | |
+ 52 | GDx | 2912 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 18,273 | |
OCT | 3032 | 19.7410 | Dominateda | |
HRT-MRA | 3061 | 19.7414 | Dominateda | |
HRT-GPS | 3071 | 19.7414 | Dominateda | |
+ 55 | GDx | 2926 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 12,260 | |
OCT | 3045 | 19.7410 | Dominateda | |
HRT-MRA | 3075 | 19.7414 | Dominateda | |
HRT-GPS | 3084 | 19.7414 | Dominateda | |
+ 58 | GDx | 2940 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 6246 | |
OCT | 3059 | 19.7410 | Dominateda | |
HRT-MRA | 3089 | 19.7414 | Dominateda | |
HRT-GPS | 3098 | 19.7414 | Dominateda | |
+ 61 | GDx | 2954 | 19.7393 | – |
Current practice | 2954 | 19.7415 | 233 | |
OCT | 3073 | 19.7410 | Dominateda | |
HRT-MRA | 3102 | 19.7414 | Dominateda | |
HRT-GPS | 3112 | 19.7414 | Dominateda | |
+ 64 | Current practice | 2954 | 19.7415 | – |
GDx | 2967 | 19.7393 | Dominateda | |
OCT | 3087 | 19.7410 | Dominateda | |
HRT-MRA | 3116 | 19.7414 | Dominateda | |
HRT-GPS | 3126 | 19.7414 | Dominateda | |
+ 67 | Current practice | 2954 | 19.7415 | – |
GDx | 2981 | 19.7393 | Dominateda | |
OCT | 3100 | 19.7410 | Dominateda | |
HRT-MRA | 3130 | 19.7414 | Dominateda | |
HRT-GPS | 3139 | 19.7414 | Dominateda |
- a
Dominated: an intervention is more costly but is less effective or as effective as an intervention that is less costly.
- Cost-effectiveness supplementary tables - Automated imaging technologies for the...Cost-effectiveness supplementary tables - Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study)
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