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Azuara-Blanco A, Banister K, Boachie C, et al. Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study). Southampton (UK): NIHR Journals Library; 2016 Jan. (Health Technology Assessment, No. 20.8.)

Appendix 7Cost-effectiveness supplementary tables

TABLE 63

Incremental cost-effectiveness for the base case with different NHS Reference Costs applied to the triage strategies

NHS Reference Cost (£)InterventionCost (£)QALYsICER
10GDx284119.7701–
OCT296719.774627,812
HRT-MRA300119.777113,807
HRT-GPS301119.7771Dominateda
Current practice308419.778098,231
13GDx285619.7701–
OCT298219.774627,784
HRT-MRA301619.777113,780
HRT-GPS302619.7771Dominateda
Current practice308419.778080,605
16GDx287219.7701–
OCT299619.774627,757
HRT-MRA303119.777113,754
HRT-GPS304019.7771Dominateda
Current practice308419.778062,979
19GDx288719.7701–
OCT301119.774627,729
HRT-MRA304619.777113,727
HRT-GPS305519.7771Dominateda
Current practice308419.778045,353
22GDx290219.7701–
OCT302619.774627,701
HRT-MRA306019.777113,700
HRT-GPS307019.7771Dominateda
Current practice308419.778027,727
25GDx291719.7701–
OCT304119.774627,673
HRT-MRA307519.777113,673
Current practice308419.778010,101
HRT-GPS308519.7771Dominateda
28GDx293219.7701–
OCT305619.774627,646
Current practice308419.77808313
HRT-MRA309019.7771Dominateda
HRT-GPS310019.7771Dominateda
31GDx294719.7701–
OCT307119.774627,618
Current practice308419.77803853
HRT-MRA310519.7771Dominateda
HRT-GPS311519.7771Dominateda
34GDx296219.7701–
Current practice308419.778015,579
OCT308619.7746Dominateda
HRT-MRA312019.7771Dominateda
HRT-GPS312919.7771Dominateda
37GDx297719.7701–
Current practice308419.778013,663
OCT310119.7746Dominateda
HRT-MRA313519.7771Dominateda
HRT-GPS314419.7771Dominateda
40GDx299219.7701–
Current practice308419.778011,747
OCT311619.7746Dominateda
HRT-MRA314919.7771Dominateda
HRT-GPS315919.7771Dominateda
43GDx300719.7701–
Current practice308419.77809831
OCT313019.7746Dominateda
HRT-MRA316419.7771Dominateda
HRT-GPS317419.7771Dominateda
46GDx302219.7701–
Current practice308419.77807315
OCT314519.7746Dominateda
HRT-MRA317919.7771Dominateda
HRT-GPS318919.7771Dominateda
49GDx303719.7701–
Current practice308419.77805999
OCT316019.7746Dominateda
HRT-MRA319419.7771Dominateda
HRT-GPS320419.7771Dominateda
52GDx305219.7701–
Current practice308419.77804083
OCT317519.7746Dominateda
HRT-MRA320919.7771Dominateda
HRT-GPS321819.7771Dominateda
55GDx306719.7701–
Current practice308419.77802168
OCT319019.7746Dominateda
HRT-MRA322419.7771Dominateda
HRT-GPS323319.7771Dominateda
58GDx308219.7701–
Current practice308419.7780252
OCT320519.7746Dominateda
HRT-MRA323819.7771Dominateda
HRT-GPS324819.7771Dominateda
61Current practice308419.7780–
GDx309719.7701Dominateda
OCT322019.7746Dominateda
HRT-MRA325319.7771Dominateda
HRT-GPS326319.7771Dominateda
64Current practice308419.7780–
GDx311219.7701Dominateda
OCT323519.7746Dominateda
HRT-MRA326819.7771Dominateda
HRT-GPS327819.7771Dominateda
67Current practice308419.7780–
GDx312719.7701Dominateda
OCT325019.7746Dominateda
HRT-MRA328319.7771Dominateda
HRT-GPS329219.7771Dominateda
70Current practice308419.7780–
GDx314219.7701Dominateda
OCT326519.7746Dominateda
HRT-MRA329819.7771Dominateda
HRT-GPS330719.7771Dominateda
73Current practice308419.7780–
GDx315719.7701Dominateda
OCT327919.7746Dominateda
HRT-MRA331319.7771Dominateda
HRT-GPS332219.7771Dominateda
76Current practice308419.7780–
GDx317219.7701Dominateda
OCT329419.7746Dominateda
HRT-MRA332719.7771Dominateda
HRT-GPS333719.7771Dominateda
79Current practice308419.7780–
GDx318719.7701Dominateda
OCT330919.7746Dominateda
HRT-MRA334219.7771Dominateda
HRT-GPS335219.7771Dominateda
82Current practice308419.7780–
GDx320219.7701Dominateda
OCT332419.7746Dominateda
HRT-MRA335719.7771Dominateda
HRT-GPS336719.7771Dominateda
85Current practice308419.7780–
GDx321719.7701Dominateda
OCT333919.7746Dominateda
HRT-MRA337219.7771Dominateda
HRT-GPS338119.7771Dominateda
a

Dominated: an intervention is more costly but is less effective or as effective as an intervention that is less costly.

TABLE 64

Incremental cost-effectiveness ratios of increasing costs of triage strategies and not treating patients diagnosed as ‘at risk’

Increasing cost of triage strategy (£)InterventionCost (£)QALYsICER
+ 10GDx271919.7393–
OCT284019.741068,260
HRT-MRA286919.741483,488
HRT-GPS287919.7414Dominateda
Current practice295419.7415488,759
+ 13GDx273319.7393–
OCT285319.741068,229
HRT-MRA288319.741483,457
HRT-GPS289319.7414Dominateda
Current practice295419.7415409,713
+ 16GDx274719.7393–
OCT286719.741068,198
HRT-MRA289719.741483,426
HRT-GPS290619.7414Dominateda
Current practice295419.7415330,667
+ 19GDx276119.7393–
OCT288119.741068,167
HRT-MRA291019.741483,396
HRT-GPS292019.7414Dominateda
Current practice295419.7415251,620
+ 22GDx277519.7393–
OCT289519.741068,137
HRT-MRA292419.741483,365
HRT-GPS293419.7414Dominateda
Current practice295419.7415172,574
+ 25GDx278819.7393–
OCT290819.741068,106
HRT-MRA293819.741483,335
HRT-GPS294719.7414Dominateda
Current practice295419.741593,527
+ 28GDx280219.7393–
OCT292219.741068,075
HRT-MRA295219.741483,304
Current practice295419.741514,481
HRT-GPS296119.7414Dominateda
+ 31GDx281619.7393–
OCT293619.741068,044
Current practice295419.741534,813
HRT-MRA296519.7414Dominateda
HRT-GPS297519.7414Dominateda
+ 34GDx283019.7393–
OCT294919.741068,014
Current practice295419.74158882
HRT-MRA297919.7414Dominateda
HRT-GPS298919.7414Dominateda
+ 37GDx284319.7393–
Current practice295419.741548,341
OCT296319.7410Dominateda
HRT-MRA299319.7414Dominateda
HRT-GPS300219.7414Dominateda
+ 40GDx285719.73930
Current practice295419.741542,328
OCT297719.7410Dominateda
HRT-MRA300619.7414Dominateda
HRT-GPS301619.7414Dominateda
+ 43GDx287119.7393–
Current practice295419.741536,314
OCT299119.7410Dominateda
HRT-MRA302019.7414Dominateda
HRT-GPS303019.7414Dominateda
+ 46GDx288519.7393–
Current practice295419.741530,300
OCT300419.7410Dominateda
HRT-MRA303419.7414Dominateda
HRT-GPS304319.7414Dominateda
+ 49GDx289819.7393–
Current practice295419.741524,287
OCT301819.7410Dominateda
HRT-MRA304819.7414Dominateda
HRT-GPS305719.7414Dominateda
+ 52GDx291219.7393–
Current practice295419.741518,273
OCT303219.7410Dominateda
HRT-MRA306119.7414Dominateda
HRT-GPS307119.7414Dominateda
+ 55GDx292619.7393–
Current practice295419.741512,260
OCT304519.7410Dominateda
HRT-MRA307519.7414Dominateda
HRT-GPS308419.7414Dominateda
+ 58GDx294019.7393–
Current practice295419.74156246
OCT305919.7410Dominateda
HRT-MRA308919.7414Dominateda
HRT-GPS309819.7414Dominateda
+ 61GDx295419.7393–
Current practice295419.7415233
OCT307319.7410Dominateda
HRT-MRA310219.7414Dominateda
HRT-GPS311219.7414Dominateda
+ 64Current practice295419.7415–
GDx296719.7393Dominateda
OCT308719.7410Dominateda
HRT-MRA311619.7414Dominateda
HRT-GPS312619.7414Dominateda
+ 67Current practice295419.7415–
GDx298119.7393Dominateda
OCT310019.7410Dominateda
HRT-MRA313019.7414Dominateda
HRT-GPS313919.7414Dominateda
a

Dominated: an intervention is more costly but is less effective or as effective as an intervention that is less costly.

Copyright © Queen’s Printer and Controller of HMSO 2016. This work was produced by Azuara-Blanco et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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Bookshelf ID: NBK338825
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