| Outcomes | No. of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with standard treatment | Risk difference with intra-operative cell salvage + post-operative cell salvage (95% CI) | ||||
| No. exposed to allogeneic blood | 230 (2 studies) | VERY LOWa,b due to risk of bias, imprecision | RR 0.69 (0.54 to 0.89) | Study population | |
| 632 per 1000 | 196 fewer per 1000 (from 70 fewer to 291 fewer) | ||||
| Mortality at up to 30 days | 196 (1 study) | VERY LOWa,c due to risk of bias, imprecision | RR 0.33 (0.03 to 3.09) | Study population | |
| 31 per 1000 | 21 fewer per 1000 (from 30 fewer to 65 more) | ||||
| Any infection | 196 (1 study) | VERY LOWa,c due to risk of bias, imprecision | RR 0.98 (0.14 to 6.82) | Study population | |
| 21 per 1000 | 0 fewer per 1000 (from 18 fewer to 120 more) | ||||
| Length of hospital stay | 196 (1 study) | VERY LOWa,c due to risk of bias, imprecision | The mean length of hospital stay in the intervention groups was 2.8 higher (2.11 lower to 7.71 higher) | ||
The majority of the evidence is at very high risk of bias.
The confidence interval crosses one MID.
The confidence interval crosses both MIDs.
From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid
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