| Outcomes | No. of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with standard treatment | Risk difference with post-operative cell salvage (95% CI) | ||||
| No. exposed to allogeneic blood | 262 (4 studies) | VERY LOWa,b due to risk of bias, imprecision | RR 0.6 (0.45 to 0.81) | Study population | |
| 390 per 1000 | 156 fewer per 1000 (from 74 fewer to 214 fewer) | ||||
| Units of allogeneic blood transfused | 60 (1 study) | VERY LOWa,b due to risk of bias, imprecision | The mean units of allogeneic blood transfused in the intervention groups was 1.02 lower (1.19 to 0.85 lower) | ||
| Mortality at up to 30 days | 50 (1 study) | VERY LOWa,c due to risk of bias, imprecision | RR 3 (0.13 to 70.3) | Study population | |
| 0 per 1000 | - | ||||
| Any infection | 90 (1 study) | VERY LOWa,b due to risk of bias, imprecision | RR 0.15 (0.02 to 1.15) | Study population | |
| 163 per 1000 | 139 fewer per 1000 (from 160 fewer to 24 more) | ||||
| Hospital length of stay | 90 (1 study) | LOWa due to risk of bias | The mean hospital length of stay in the intervention groups was 7.13 lower (9.12 to 5.14 lower) | ||
The majority of the evidence was at very high risk of bias.
The confidence interval crosses one MID.
The confidence interval crosses both MIDs.
From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid
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