Table 46Tranexamic acid versus standard treatment

OutcomesNo. of Participants
(studies)
Follow up
Quality of the evidence
(GRADE)
Relative effect
(95% CI)
Anticipated absolute effects
Risk with Standard treatmentRisk difference with TXA (95% CI)
Post-operative blood loss - post 2003120
(1 study)
MODERATEa
due to risk of bias
The mean post-operative blood loss - post 2003 in the intervention groups was 16 lower (21.13 to 10.87 lower)
Length of stay83
(1 study)
LOWb
due to risk of bias, imprecision
The mean length of stay in the intervention groups was 0.1 higher (0.37 lower to 0.57 higher)
a

Majority of the evidence was at high risk of bias.

b

Confidence interval crosses one MID.

From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid

Cover of Blood Transfusion
Blood Transfusion.
NICE Guideline, No. 24.
National Clinical Guideline Centre (UK).
Copyright © 2015 National Clinical Guideline Centre.

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