| Outcomes | No. of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with intra-operative cell salvage | Risk difference with intra-operative cell salvage + TXA (95% CI) | ||||
| No. exposed to allogeneic blood | 147 (1 study) | VERY LOWa,b due to risk of bias, imprecision | RR 0.78 (0.5 to 1.2) | Study population | |
| 405 per 1000 | 89 fewer per 1000 (from 203 fewer to 81 more) | ||||
| Units of blood transfused | 147 (1 study) | VERY LOWa,c due to risk of bias, imprecision | The mean units of blood transfused in the intervention groups was 0.46 lower (1.1 lower to 0.18 higher) | ||
| Length of stay in hospital | 147 (1 study) | VERY LOWa,c due to risk of bias, imprecision | The mean length of stay in hospital in the intervention groups was 0.72 higher (0.85 lower to 2.29 higher) | ||
Majority of the evidence was at very high risk of bias.
Confidence interval crosses one MID.
Confidence interval crosses both MIDs.
From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid
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