Table 34, Intra-operative cell salvage plus post-operative cell salvage plus tranexamic acid versus tranexamic acid - Blood Transfusion - NCBI Bookshelf

Warning: The NCBI web site requires JavaScript to function. more...

Table 34Intra-operative cell salvage plus post-operative cell salvage plus tranexamic acid versus tranexamic acid

Outcomes	No. of Participants (studies) Follow up	Quality of the evidence (GRADE)	Relative effect (95% CI)	Anticipated absolute effects
Outcomes	No. of Participants (studies) Follow up	Quality of the evidence (GRADE)	Relative effect (95% CI)	Risk with TXA	Risk difference with intra-operative cell salvage + post-operative cell salvage + TXA (95% CI)
No. exposed to allogeneic blood	213 (1 study)	VERY LOW^a^,^b due to risk of bias, imprecision	RR 1.02 (0.68 to 1.54)	Study population
No. exposed to allogeneic blood	213 (1 study)	VERY LOW^a^,^b due to risk of bias, imprecision	RR 1.02 (0.68 to 1.54)	297 per 1000	6 more per 1000 (from 95 fewer to 161 more)
Any infection	213 (1 study)	VERY LOW^a^,^b due to risk of bias, imprecision	RR 1.31 (0.41 to 4.15)	Study population
Any infection	213 (1 study)	VERY LOW^a^,^b due to risk of bias, imprecision	RR 1.31 (0.41 to 4.15)	45 per 1000	14 more per 1000 (from 27 fewer to 142 more)

a: The majority of the evidence is at very high risk of bias.
b: The confidence interval crosses both MIDs.

From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid

Cover of Blood Transfusion

Blood Transfusion.

NICE Guideline, No. 24.

National Clinical Guideline Centre (UK).

London: National Institute for Health and Care Excellence (NICE); 2015 Nov.

Copyright © 2015 National Clinical Guideline Centre.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.