From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid
Copyright © 2015 National Clinical Guideline Centre.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
National Clinical Guideline Centre (UK). Blood Transfusion. London: National Institute for Health and Care Excellence (NICE); 2015 Nov. (NICE Guideline, No. 24.)
Table 34Intra-operative cell salvage plus post-operative cell salvage plus tranexamic acid versus tranexamic acid
| Outcomes | No. of Participants (studies) Follow up | Quality of the evidence (GRADE) | Relative effect (95% CI) | Anticipated absolute effects | |
|---|---|---|---|---|---|
| Risk with TXA | Risk difference with intra-operative cell salvage + post-operative cell salvage + TXA (95% CI) | ||||
| No. exposed to allogeneic blood | 213 (1 study) | VERY LOWa,b due to risk of bias, imprecision | RR 1.02 (0.68 to 1.54) | Study population | |
| 297 per 1000 | 6 more per 1000 (from 95 fewer to 161 more) | ||||
| Any infection | 213 (1 study) | VERY LOWa,b due to risk of bias, imprecision | RR 1.31 (0.41 to 4.15) | Study population | |
| 45 per 1000 | 14 more per 1000 (from 27 fewer to 142 more) | ||||
- a
The majority of the evidence is at very high risk of bias.
- b
The confidence interval crosses both MIDs.
- Table 34, Intra-operative cell salvage plus post-operative cell salvage plus tra...Table 34, Intra-operative cell salvage plus post-operative cell salvage plus tranexamic acid versus tranexamic acid - Blood Transfusion
- PREDICTED: Homo sapiens treacle ribosome biogenesis factor 1 (TCOF1), transcript...PREDICTED: Homo sapiens treacle ribosome biogenesis factor 1 (TCOF1), transcript variant X25, mRNAgi|2462604122|ref|XM_054353364.1|Nucleotide
- LOC102547034 40S ribosomal protein S23-like [Rattus norvegicus]LOC102547034 40S ribosomal protein S23-like [Rattus norvegicus]Gene ID:102547034Gene
- Dynll1-ps3 dynein light chain LC8-type 1, pseudogene 3 [Rattus norvegicus]Dynll1-ps3 dynein light chain LC8-type 1, pseudogene 3 [Rattus norvegicus]Gene ID:108352398Gene
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