Table 33, Intra-operative cell salvage plus post-operative cell salvage plus tranexamic acid versus intra-operative cell salvage plus post-operative cell salvage - Blood Transfusion - NCBI Bookshelf

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Table 33Intra-operative cell salvage plus post-operative cell salvage plus tranexamic acid versus intra-operative cell salvage plus post-operative cell salvage

Outcomes	No. of Participants (studies) Follow up	Quality of the evidence (GRADE)	Relative effect (95% CI)	Anticipated absolute effects
Outcomes	No. of Participants (studies) Follow up	Quality of the evidence (GRADE)	Relative effect (95% CI)	Risk with intra-operative cell salvage + postoperative cell salvage	Risk difference with intra-operative cell salvage + post-operative cell salvage + TXA (95% CI)
No. exposed to allogeneic blood	100 (1 study)	VERY LOW^a^,^b due to risk of bias, imprecision	RR 0.93 (0.49 to 1.77)	Study population
No. exposed to allogeneic blood	100 (1 study)	VERY LOW^a^,^b due to risk of bias, imprecision	RR 0.93 (0.49 to 1.77)	280 per 1000	20 fewer per 1000 (from 143 fewer to 216 more)
Units of blood transfused	27 (1 study)	VERY LOW^a^,^c due to risk of bias, imprecision			The mean units of blood transfused in the intervention groups was 0.25 higher (0.32 lower to 0.82 higher)
Mortality at 30 days	100 (1 study)	LOW^a due to risk of bias	Not estimable

a: The majority of the evidence was at very high risk of bias.
b: The confidence interval crosses both MIDs.
c: The confidence interval crosses one MID.

From: 6, Alternatives to blood transfusion for patients having surgery: Cell salvage and tranexamic acid

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Blood Transfusion.

NICE Guideline, No. 24.

National Clinical Guideline Centre (UK).

London: National Institute for Health and Care Excellence (NICE); 2015 Nov.

Copyright © 2015 National Clinical Guideline Centre.

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