Table 5.

Key Points- Cholestatic Disease

Plasma total cholesterol concentrations are commonly elevated in the setting of cholestasis.
Lipoprotein-X is an abnormal lipoprotein that circulates in patients with cholestasis and is primarily responsible for the elevations in plasma total cholesterol concentrations.
Elevations in plasma cholesterol concentrations due to cholestasis do not appear to confer excess CVD risk.
Patients with cholestatic disorders may be candidates for lipid lowering therapy if they are otherwise at risk for CVD.

From: Lipid and Lipoprotein Metabolism in Liver Disease

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